Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | MVD | P53602 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1887004 | 0.88 | MEN1 (0.31) | MEN1KMT2AHPGDMAPTMAPK1 | |
| SCHEMBL10304981 | 0.88 | PIK3CD (0.35) | MEN1KMT2AHPGDMAPTRAB9A | |
| SCHEMBL6097999 | 0.88 | PDK2 (0.38) | MEN1KMT2AHPGDMAPTMAPK1 | |
| SCHEMBL12947904 | 0.88 | ALDH1A1 (0.33) | MEN1KMT2AHPGDMAPTMAPK1 | |
| SCHEMBL20369122 | 0.86 | MEN1 (0.30) | MEN1KMT2AHPGDMAPT | |
| SCHEMBL25615723 | 0.84 | ALDH1A1 (0.35) | ALDH1A1SLC6A4BCHEACHECHRM2 | |
| SCHEMBL6097360 | 0.84 | SLC6A4 (0.33) | SLC6A4BCHEACHECHRM2CHRM1 | |
| SCHEMBL6097372 | 0.84 | SLC6A4 (0.33) | SLC6A4BCHEACHECHRM2CHRM1 | |
| SCHEMBL21842634 | 0.84 | ALDH1A1 (0.40) | HPGDMAPTSMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL21477775 | 0.83 | EPHX2 (0.45) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8106191-B2 | Compounds based on N- acyl-pipecolyl and N-acyl-prolyl ligand moieties for multimerizing chimeric proteins containing immunophilin-derived domains | ARIAD PHARMACEUTICALS, INC. (US) | 2012-01-31 | — | — | US | disclosed |