SCHEMBL10111202

SCHEMBL10111202

Cc1c(N(C)C)cc(C)c2[nH]cnc12

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDPK1 O15530 4/20 0.41
CHEK1 O14757 1/20 0.41
AURKA O14965 1/20 0.41
CHEK2 O96017 1/20 0.41
HSP90AA1 P07900 1/20 0.41
HSP90AB1 P08238 1/20 0.41
PRKACA P17612 1/20 0.41
CCNE1 P24864 1/20 0.41
CDK2 P24941 1/20 0.41
MARK3 P27448 1/20 0.41
RPS6KA3 P51812 1/20 0.41
PRKCD Q05655 1/20 0.41
LRRK2 Q5S007 1/20 0.41
MARK2 Q7KZI7 1/20 0.41
PARP1 P09874 2/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
CSNK2A1 P68400 3/20 0.34
CSNK2A2 P19784 2/20 0.34
RAB9A P51151 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6142564 0.76 PDPK1 (0.37) PDPK1LRRK2PARP1MEN1KMT2A
SCHEMBL25647646 0.73 ABL1 (0.44) PDPK1PARP1MEN1KMT2ACSNK2A1
SCHEMBL27406579 0.71
SCHEMBL10111018 0.70 KDM4E (0.39) PDPK1AURKAPARP1MEN1KMT2A
SCHEMBL6142538 0.69 MEN1 (0.51) PDPK1PARP1MEN1KMT2AALDH1A1
SCHEMBL12618885 0.69 PDPK1 (0.44) PDPK1CHEK1AURKACHEK2HSP90AA1
SCHEMBL18819883 0.68 PDPK1 (0.48) PDPK1CHEK1AURKACHEK2HSP90AA1
SCHEMBL6142543 0.68 PLAU (0.33) PDPK1PARP1MEN1KMT2ACSNK2A1
SCHEMBL4560164 0.67 PARP1 (0.46) PDPK1PARP1MEN1KMT2ACSNK2A1
SCHEMBL6142539 0.66 PDPK1 (0.30) PDPK1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9758688-B2 Composition for forming conductive film SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-09-12 US disclosed
US-9704612-B2 Composition of silver-conjugated compound composite SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-07-11 US disclosed
US-9536633-B2 Metallic composite and composition thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-01-03 US disclosed
US-9412487-B2 Silver-(conjugated compound) composite SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-08-09 US disclosed
US-20150275015-A1 COMPOSITION FOR FORMING CONDUCTIVE FILM SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-10-01 US disclosed
US-8866134-B2 Light-emitting device and photovoltaic cell, and method for manufacturing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-10-21 US disclosed
US-20130099224-A1 LIGHT-EMITTING DEVICE AND PHOTOVOLTAIC CELL, AND METHOD FOR MANUFACTURING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-04-25 US disclosed
US-20120168693-A1 SILVER-(CONJUGATED COMPOUND) COMPOSITE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-07-05 US disclosed
US-20120032121-A1 METALLIC COMPOSITE AND COMPOSITION THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-02-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120032121-A1 METALLIC COMPOSITE AND COMPOSITION THEREOF CDH1, EPCAM, CD4 PDPK1 4220/4885CHEK1 2049/4885AURKA 3530/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.