SCHEMBL101122

SCHEMBL101122

[CH2]C(C)CCCCCCCCCCCCCCC

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 1/20 0.50
TSHR P16473 1/20 0.47
THRB P10828 1/20 0.47
GPR84 Q9NQS5 3/20 0.46
SPHK1 Q9NYA1 1/20 0.46
FFAR1 O14842 1/20 0.46
LMNA P02545 1/20 0.46
DNM1 Q05193 2/20 0.46
ADH1B P00325 1/20 0.43
ADH1C P00326 1/20 0.43
ADH1A P07327 1/20 0.43
ADH4 P08319 1/20 0.43
ADH7 P40394 1/20 0.43
ACE2 Q9BYF1 1/20 0.41
FDPS P14324 3/20 0.41
CA1 P00915 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6348875 1.00
SCHEMBL200216 1.00 OPRM1 (0.50) OPRM1TSHRTHRBGPR84SPHK1
SCHEMBL100862 1.00 OPRM1 (0.50) OPRM1TSHRTHRBGPR84SPHK1
SCHEMBL2201684 1.00 OPRM1 (0.50) OPRM1TSHRTHRBGPR84SPHK1
SCHEMBL201087 1.00 OPRM1 (0.50) OPRM1TSHRTHRBGPR84SPHK1
SCHEMBL2201024 1.00 OPRM1 (0.50) OPRM1TSHRTHRBGPR84SPHK1
SCHEMBL2201062 1.00 OPRM1 (0.50) OPRM1TSHRTHRBGPR84SPHK1
SCHEMBL21899376 1.00 OPRM1 (0.50) OPRM1TSHRTHRBGPR84SPHK1
SCHEMBL22407240 1.00 OPRM1 (0.50) OPRM1TSHRTHRBGPR84SPHK1
SCHEMBL26044 1.00 OPRM1 (0.50) OPRM1TSHRTHRBGPR84SPHK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 115 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7592351-B2 Substituted imidazo[1,2-a]pyridine compounds and pharmaceutical preparations containing substituted imidazo[1,2-a]pyridine compounds GRUENENTHAL GMBH (DE) 2009-09-22 US claimed
US-20070099896-A1 Substituted imidazo[1,2-a]pyridine compounds and pharmaceutical preparations containing substituted imidazo[1,2-a]pyridine compounds GRUENENTHAL GMBH (DE) 2007-05-03 US claimed
EP-1756105-A1 SUBSTITUTED IMIDAZO[1,2-A]PYRIDINE COMPOUNDS AND DRUGS CONTAINING SUBSTITUTED IMIDAZO[1,2-A]PYRIDINE COMPOUNDS Grünenthal GmbH (DE) 2007-02-28 EP claimed
WO-2005105798-A1 SUBSTITUTED IMIDAZO[1,2-A]PYRIDINE COMPOUNDS AND DRUGS CONTAINING SUBSTITUTED IMIDAZO[1,2-A]PYRIDINE COMPOUNDS Grünenthal GmbH (DE) 2005-11-10 WO claimed
JP-59110640-A None JP disclosed
CN-118215651-A Method for producing isocyanate compound, method for producing urethane compound, method for recovering amine compound, and isocyanate composition 旭化成株式会社 2024-06-18 CN disclosed
CN-118201905-A Cationic lipid 武田药品工业株式会社 2024-06-14 CN disclosed
CN-113710367-B Method for flotation of silicate-containing iron ore with cationic collector 巴斯夫欧洲公司 2024-05-24 CN disclosed
WO-2024018762-A1 PH-SENSITIVE CATIONIC LIPID AND LIPID NANOPARTICLE 国立大学法人北海道大学 2024-01-25 WO disclosed
WO-2024018761-A1 NEUTRAL LIPID AND LIPID NANOPARTICLE 国立大学法人北海道大学 2024-01-25 WO disclosed
CN-114207210-B Fiber treating agent for nonwoven fabric 三吉油脂株式会社 2023-09-19 CN disclosed
CN-116685409-A Method for flotation of silicate-containing iron ore 巴斯夫欧洲公司 2023-09-01 CN disclosed
US-5120738-A Cardiovascular disorders FUJIREBIO INC. (JP) 1992-06-09 US disclosed
EP-0421441-A2 Pantothenic acid derivatives FUJIREBIO INC. (JP) 1991-04-10 EP disclosed
US-4798721-A LATEX, WATER INSOLUBLE MONOMERS KAO CORPORATION (JP) 1989-01-17 US disclosed
US-4676915-A Antistatic composition and detergent compositions containing antistatic components COLGATE-PALMOLIVE COMPANY (US) 1987-06-30 US disclosed
EP-0214626-A2 Hair cosmetic composition Kao Corporation (JP) 1987-03-18 EP disclosed
US-4626429-A Conditioning of hair with amides of trialkylacetic acids COLGATE-PALMOLIVE COMPANY (US) 1986-12-02 US disclosed
JP-S59110640-A 2-METHYLHEPTADECYL GLYCERYL ETHER KAO CORP 1984-06-26 JP disclosed
US-4331683-A SENSITIZATION, ANTIALLERGENS PFIZER INC. (US) 1982-05-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070099896-A1 Substituted imidazo[1,2-a]pyridine compounds and pharmaceutical preparations containing substituted imidazo[1,2-a]pyridine compounds GIPR, CHUK, ITPA OPRM1 1842/4885TSHR 1545/4885THRB 3826/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.