Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1262342 | 0.84 | ALDH1A1 (0.41) | TLR4TP53 | |
| SCHEMBL680912 | 0.84 | ALDH1A1 (0.41) | TLR4TP53 | |
| SCHEMBL29807013 | 0.78 | ALDH1A1 (0.46) | TLR4TP53 | |
| SCHEMBL9122696 | 0.78 | ALDH1A1 (0.46) | TLR4TP53 | |
| SCHEMBL12847556 | 0.77 | TLR4 (0.31) | TLR4 | |
| SCHEMBL11014967 | 0.75 | MAPK1 (0.50) | — | |
| SCHEMBL6904973 | 0.75 | ALDH1A1 (0.39) | TLR4TP53 | |
| SCHEMBL5796691 | 0.75 | ALDH1A1 (0.42) | TLR4TP53 | |
| SCHEMBL30410792 | 0.72 | CYP2D6 (0.46) | TLR4 | |
| SCHEMBL190832 | 0.71 | TLR4 (0.34) | TLR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012135749-A2 | BIOMARKERS FOR PREDICTING SENSITIVITY TO CANCER TREATMENTS | GENENTECH, INC. (US) | 2012-10-04 | — | — | WO | disclosed |
| WO-2012088254-A1 | AUTOPHAGY INDUCER AND INHIBITOR COMBINATION THERAPY FOR THE TREATMENT OF NEOPLASMS | GENENTECH, INC. (US) | 2012-06-28 | — | — | WO | disclosed |