Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.67 |
| ▸ | HTT | P42858 | 2/20 | 0.67 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6954997 | 0.82 | MAPT (0.75) | MAPTHTTADRA2CALDH1A1MEN1 | |
| SCHEMBL29379717 | 0.80 | MAPT (1.00) | MAPTHTTADRA2CALDH1A1MEN1 | |
| SCHEMBL76608 | 0.80 | MAPT (1.00) | MAPTHTTADRA2CALDH1A1MEN1 | |
| SCHEMBL2971434 | 0.80 | MAPT (0.73) | MAPTHTTADRA2CALDH1A1MEN1 | |
| SCHEMBL7559659 | 0.79 | MAPT (0.76) | MAPTHTTADRA2CALDH1A1MEN1 | |
| SCHEMBL30525803 | 0.78 | MAPT (0.95) | MAPTHTTADRA2CALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL2342540 | 0.78 | MAPT (0.95) | MAPTHTTADRA2CALDH1A1MEN1 | |
| SCHEMBL29512293 | 0.78 | MAPT (0.70) | MAPTHTTADRA2CALDH1A1MEN1 | |
| SCHEMBL29512292 | 0.78 | MAPT (0.70) | MAPTHTTADRA2CALDH1A1MEN1 | |
| SCHEMBL442009 | 0.78 | MAPT (0.70) | MAPTHTTADRA2CALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3303317-B1 | METHODS AND COMPOSITIONS FOR INHIBITING THE INTERACTION OF MENIN WITH MLL PROTEINS | KURA ONCOLOGY INC (US) | 2021-10-06 | — | — | EP | disclosed |
| US-9929361-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2018-03-27 | — | — | US | disclosed |
| US-20120028912-A1 | Methods of modulating bromodomains | J.David Gladstone Institute | 2012-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120028912-A1 | Methods of modulating bromodomains | BAZ2A, BRPF3, BRD3 | MAPT 1884/4885HTT 3530/4885ADRA2C 3835/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.