Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.75 |
| ▸ | HTT | P42858 | 2/20 | 0.75 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA3 | P07451 | 1/20 | 0.55 |
| ▸ | CA4 | P22748 | 1/20 | 0.55 |
| ▸ | CA6 | P23280 | 1/20 | 0.55 |
| ▸ | CA5A | P35218 | 1/20 | 0.55 |
| ▸ | CA7 | P43166 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.55 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.47 |
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7559659 | 0.88 | MAPT (0.76) | MAPTHTTCA12CA3CA4 | |
| SCHEMBL29379717 | 0.86 | MAPT (1.00) | MAPTHTTALDH1A1TSHRGAA | |
| SCHEMBL76608 | 0.86 | MAPT (1.00) | MAPTHTTALDH1A1TSHRGAA | |
| SCHEMBL7149996 | 0.86 | MAPT (0.73) | MAPTHTTCA12CA3CA4 | |
| SCHEMBL18389925 | 0.84 | MAPT (0.70) | MAPTHTTCA12CA3CA4 | |
| Hydrochloric Acid SCHEMBL2342540 | 0.84 | MAPT (0.95) | MAPTHTTALDH1A1TSHRGAA | |
| SCHEMBL30525803 | 0.84 | MAPT (0.95) | MAPTHTTALDH1A1TSHRGAA | |
| SCHEMBL7996193 | 0.83 | MAPT (0.52) | MAPTHTTCA12CA3CA4 | |
| SCHEMBL10113252 | 0.82 | MAPT (0.67) | MAPTHTTALDH1A1TSHRGAA | |
| SCHEMBL22171683 | 0.80 | CA12 (0.62) | MAPTHTTCA12CA3CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117567294-A | Preparation method of anti-aging agent N-phenyl-N' - (1-methyl-2-phenyl) ethyl p-phenylenediamine | 山东阳谷华泰化工股份有限公司 | 2024-02-20 | — | — | CN | claimed |
| CN-117567294-A | Preparation method of anti-aging agent N-phenyl-N' - (1-methyl-2-phenyl) ethyl p-phenylenediamine | 山东阳谷华泰化工股份有限公司 | 2024-02-20 | — | — | CN | disclosed |
| CN-117567294-A | Preparation method of anti-aging agent N-phenyl-N' - (1-methyl-2-phenyl) ethyl p-phenylenediamine | 山东阳谷华泰化工股份有限公司 | 2024-02-20 | — | — | CN | disclosed |
| WO-2021116686-A1 | METHYL 2-ALLYL-1 -METHYL-3-OXOINDOLINE-2-CARBOXYLATE AND 9A-ALLYL-1,2,3,9A-TETRAHYDRO-9H-PYRROLO[1,2-A]INDOL-9-ONE DERIVATIVES AND RELATED COMPOUNDS FOR USE AS FLUORESCENT MARKERS FOR LABELLING OF DRUGS, AMINO ACIDS AN PROTEINS | UNIVERSITY OF LANCASTER (GB) | 2021-06-17 | — | — | WO | disclosed |
| US-9637489-B2 | Immune system modulators | JANUS BIOTHERAPEUTICS, INC. (US) | 2017-05-02 | — | — | US | disclosed |
| US-9353115-B2 | Immune system modulators | JANUS BIOTHERAPEUTICS, INC. (US) | 2016-05-31 | — | — | US | disclosed |
| EP-2713737-B1 | NOVEL IMMUNE SYSTEM MODULATORS | JANUS BIOTHERAPEUTICS INC (US) | 2016-04-20 | — | — | EP | disclosed |
| US-20140107115-A1 | NOVEL IMMUNE SYSTEM MODULATORS | JANUS BIOTHERAPEUTICS, INC. (US) | 2014-04-17 | — | — | US | disclosed |
| US-20120149661-A1 | TETRA-SUBSTITUTED HETEROARYL COMPOUNDS AND THEIR USE AS MDM2 AND/OR MDM4 MODULATORS | NOVARTIS AG (CH) | 2012-06-14 | — | — | US | disclosed |
| WO-2011023677-A1 | TETRA-SUBSTITUTED HETEROARYL COMPOUNDS AND THEIR USE AS MDM2 AND/OR MDM4 MODULATORS | NOVARTIS AG (CH) | 2011-03-03 | — | — | WO | disclosed |
| CN-101394830-A | Cosmetic agents comprising purine and/or purine derivatives I | HENKEL KGAA (DE) | 2009-03-25 | — | — | CN | disclosed |
| EP-1243582-A1 | QUINOLINE AND QUINAZOLINE DERIVATIVES AND DRUGS CONTAINING THE SAME | KIRIN BEER KABUSHIKI KAISHA (JP) | 2002-09-25 | — | — | EP | disclosed |
| US-6294615-B1 | AS FLOCCULATING AGENT FOR ORGANIC SLUDGE | TOSCH CORPORATION (JP) | 2001-09-25 | — | — | US | disclosed |
| CN-1051670-A | Contain the dyeing composition for keratinous fibres of oxidation dye parent and amino indole colour former, the colouring method that uses these compositionss and noval chemical compound | OREAL (FR) | 1991-05-29 | — | — | CN | disclosed |
| US-4356322-A | ADRENERGIC STIMULANTS; CARDIOTONIC AGENTS | VEB ARZNEIMITTELWERK DRESDEN (DD) | 1982-10-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149661-A1 | TETRA-SUBSTITUTED HETEROARYL COMPOUNDS AND THEIR USE AS MDM2 AND/OR MDM4 MODULATORS | MDM4, MDM2, TP53 | MAPT 582/4885HTT 82/4885CA12 4681/4885 |
| US-20140107115-A1 | NOVEL IMMUNE SYSTEM MODULATORS | HLA-DRB1, CD47, MYD88 | MAPT 2510/4885HTT 2763/4885CA12 1694/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.