Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL1011339

CCCCCCCC(=O)OCC(O)C(C)(C)C.N

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.65
LMNA P02545 2/20 0.61
KDM4E B2RXH2 1/20 0.61
DUSP3 P51452 1/20 0.61
MEN1 O00255 1/20 0.61
KMT2A Q03164 1/20 0.61
ALDH1A1 P00352 1/20 0.58
DGKA P23743 2/20 0.55
PRKCA P17252 3/20 0.54
PRKCE Q02156 1/20 0.54
PRKCQ Q04759 1/20 0.54
PRKCD Q05655 1/20 0.54
LPAR1 Q92633 2/20 0.54
LPAR4 Q99677 2/20 0.54
LPAR2 Q9HBW0 2/20 0.54
LPAR3 Q9UBY5 2/20 0.54
ENPP2 Q13822 2/20 0.54
LPAR6 P43657 1/20 0.54
LPAR5 Q9H1C0 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18195604 0.83 MAPT (0.64) MAPTLMNAKDM4EDUSP3MEN1
SCHEMBL18195602 0.83 MAPT (0.64) MAPTLMNAKDM4EDUSP3MEN1
SCHEMBL18195605 0.83 MAPT (0.64) MAPTLMNAKDM4EDUSP3MEN1
SCHEMBL18195603 0.83 MAPT (0.64) MAPTLMNAKDM4EDUSP3MEN1
SCHEMBL22601528 0.81 MAPT (0.67) MAPTLMNAKDM4EDUSP3MEN1
SCHEMBL19257810 0.81 LMNA (0.77) MAPTLMNAKDM4EDUSP3MEN1
SCHEMBL2183839 0.80 LMNA (0.83) MAPTLMNAKDM4EDUSP3MEN1
SCHEMBL3941258 0.80 LMNA (0.83) MAPTLMNAKDM4EDUSP3MEN1
SCHEMBL896977 0.80 LMNA (0.83) MAPTLMNAKDM4EDUSP3MEN1
SCHEMBL2734722 0.80 LMNA (0.83) MAPTLMNAKDM4EDUSP3MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2970571-B1 POLYESTER POLYOLS IMPARTING IMPROVED FLAMMABILITY PROPERTIES STEPAN CO (US) 2020-11-25 EP disclosed
US-20190071533-A1 POLYESTER POLYOLS IMPARTING IMPROVED FLAMMABILITY PROPERTIES STEPAN CO (US) 2019-03-07 US disclosed
EP-2970571-A1 POLYESTER POLYOLS IMPARTING IMPROVED FLAMMABILITY PROPERTIES Stepan Company (US) 2016-01-20 EP disclosed
US-20160002386-A1 POLYESTER POLYOLS IMPARTING IMPROVED FLAMMABILITY PROPERTIES STEPAN CO (US) 2016-01-07 US disclosed
WO-2014150207-A1 POLYESTER POLYOLS IMPARTING IMPROVED FLAMMABILITY PROPERTIES STEPAN COMPANY (US) 2014-09-25 WO disclosed
EP-1984415-B1 COMPATIBILIZING SURFACTANTS FOR POLYURETHANE POLYOLS AND RESINS STEPAN CO (US) 2011-01-05 EP disclosed
US-20090312447-A1 COMPATIBILIZING SURFACTANTS FOR POLYURETHANE POLYOLS AND RESINS STEPAN COMPANY (US) 2009-12-17 US disclosed
EP-1984415-A4 COMPATIBILIZING SURFACTANTS FOR POLYURETHANE POLYOLS AND RESINS STEPAN CO (US) 2009-03-04 EP disclosed
EP-1994070-A1 SULFONATED AROMATIC POLYESTER POLYOL CMPOSITIONS Oxid, L.P. (US) 2008-11-26 EP disclosed
EP-1984415-A1 COMPATIBILIZING SURFACTANTS FOR POLYURETHANE POLYOLS AND RESINS STEPAN COMPANY (US) 2008-10-29 EP disclosed
WO-2007100489-A1 SULFONATED AROMATIC POLYESTER POLYOL CMPOSITIONS OXID, L.P. (US) 2007-09-07 WO disclosed
US-20070208096-A1 Sulfonated aromatic polyester polyol compositions OXID L.P. 2007-09-06 US disclosed
WO-2007094780-A1 COMPATIBILIZING SURFACTANTS FOR POLYURETHANE POLYOLS AND RESINS STEPAN COMPANY (US) 2007-08-23 WO disclosed
US-6359022-B1 USED TO PRODUCE RIGID, CLOSED-CELL POLYURETHANE- AND POLYISOCYANURATE-BASED FOAMS STEPAN COMPANY 2002-03-19 US disclosed
EP-1171500-A1 PENTANE COMPATIBLE POLYESTER POLYOLS STEPAN COMPANY (US) 2002-01-16 EP disclosed
WO-2000061654-A1 PENTANE COMPATIBLE POLYESTER POLYOLS STEPAN COMPANY (US) 2000-10-19 WO disclosed
EP-0742241-A2 Improved processability of hydrocarbon blown, polyisocyanate based foams through use of a compatibilizing agent BASF CORPORATION (US) 1996-11-13 EP disclosed