Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CPT1A | P50416 | 8/20 | 0.42 |
| ▸ | CPT1B | Q92523 | 8/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | SCD | O00767 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4932516 | 0.83 | ALDH1A1 (0.45) | ALDH1A1RAB9ACPT1ACPT1BLMNA | |
| SCHEMBL10114592 | 0.83 | SCD (0.48) | RAB9ACPT1ACPT1BLMNASCD | |
| SCHEMBL10114477 | 0.82 | GRM5 (0.46) | ALDH1A1RAB9ACPT1ACPT1BLMNA | |
| SCHEMBL4757358 | 0.71 | MAPT (0.50) | ALDH1A1RAB9ALMNASCDMAPT | |
| SCHEMBL27713512 | 0.69 | MAPT (0.53) | LMNASCDMAPTADORA3CYP1A2 | |
| SCHEMBL10114444 | 0.68 | MAPT (0.40) | ALDH1A1RAB9ALMNANPSR1HSD17B10 | |
| SCHEMBL4938271 | 0.66 | SCD (0.48) | RAB9ACPT1ACPT1BLMNASCD | |
| SCHEMBL16257639 | 0.66 | PDE5A (0.40) | ALDH1A1LMNANPSR1HSD17B10MAPT | |
| SCHEMBL10131601 | 0.65 | GRM5 (0.47) | LMNAMAPTSMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL10114623 | 0.64 | ALDH1A1 (0.41) | ALDH1A1RAB9ALMNANPSR1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8124632-B2 | Alkylsulfonyl-substituted thiazolide compounds | ROMARK LABORATORIES, L.C. (US) | 2012-02-28 | — | — | US | disclosed |
| US-20090036467-A1 | ALKYLSULFONYL-SUBSTITUTED THIAZOLIDE COMPOUNDS | ROMARK LABORATORIES L.C. | 2009-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090036467-A1 | ALKYLSULFONYL-SUBSTITUTED THIAZOLIDE COMPOUNDS | HAVCR2, EIF2AK2, AADAC | ALDH1A1 1605/4885RAB9A 1694/4885CPT1A 1322/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.