SCHEMBL10114835

SCHEMBL10114835

c1ccc(N(c2ccccc2)c2ccc(-c3cc(-n4c5ccccc5c5ccccc54)cc(-n4c5ccccc5c5ccccc54)c3)cc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 4/20 0.48
KDM4E B2RXH2 2/20 0.48
ATM Q13315 2/20 0.48
HDAC4 P56524 1/20 0.37
ALDH1A1 P00352 5/20 0.36
MAPT P10636 2/20 0.36
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
TSPO P30536 1/20 0.35
APP P05067 2/20 0.34
AKR1C4 P17516 1/20 0.32
AKR1C3 P42330 1/20 0.32
AKR1C2 P52895 1/20 0.32
AKR1C1 Q04828 1/20 0.32
KMT2A Q03164 4/20 0.32
MAPK8 P45983 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24743802 0.97 L3MBTL1 (0.48) L3MBTL1KDM4EATMHDAC4ALDH1A1
SCHEMBL10029876 0.97 L3MBTL1 (0.48) L3MBTL1KDM4EATMHDAC4ALDH1A1
SCHEMBL26487702 0.95 L3MBTL1 (0.47) L3MBTL1KDM4EATMHDAC4ALDH1A1
SCHEMBL24948750 0.95 L3MBTL1 (0.47) L3MBTL1KDM4EATMHDAC4ALDH1A1
SCHEMBL26488657 0.94 L3MBTL1 (0.48) L3MBTL1KDM4EATMHDAC4ALDH1A1
SCHEMBL23451077 0.94 L3MBTL1 (0.48) L3MBTL1KDM4EATMHDAC4ALDH1A1
SCHEMBL24561981 0.93 L3MBTL1 (0.42) L3MBTL1KDM4EATMHDAC4ALDH1A1
SCHEMBL6372450 0.92 L3MBTL1 (0.44) L3MBTL1KDM4EATMHDAC4ALDH1A1
SCHEMBL26488660 0.91 ATM (0.46) L3MBTL1KDM4EATMHDAC4ALDH1A1
SCHEMBL24725451 0.91 L3MBTL1 (0.46) L3MBTL1KDM4EATMHDAC4ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8318323-B2 Polycyclic compounds and organic electroluminescence device employing the same IDEMITSU KOSAN CO., LTD. (JP) 2012-11-27 US disclosed
US-8318323-B2 Polycyclic compounds and organic electroluminescence device employing the same IDEMITSU KOSAN CO., LTD. (JP) 2012-11-27 US disclosed
US-8106391-B2 Organic EL device IDEMITSU KOSAN CO., LTD. (JP) 2012-01-31 US disclosed
US-8106391-B2 Organic EL device IDEMITSU KOSAN CO., LTD. (JP) 2012-01-31 US disclosed
US-20100219404-A1 ORGANIC EL DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2010-09-02 US disclosed
US-20100219404-A1 ORGANIC EL DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2010-09-02 US disclosed