Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | UBE2M | P61081 | 1/20 | 0.41 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14627688 | 1.00 | HSD17B10 (0.51) | HSD17B10GAAJAK2GRIA2ALDH1A1 | |
| SCHEMBL10133458 | 1.00 | HSD17B10 (0.51) | HSD17B10GAAJAK2GRIA2ALDH1A1 | |
| SCHEMBL13204378 | 1.00 | HSD17B10 (0.51) | HSD17B10GAAJAK2GRIA2ALDH1A1 | |
| SCHEMBL14418511 | 0.92 | HSD17B10 (0.42) | HSD17B10GAAJAK2GRIA2ALDH1A1 | |
| SCHEMBL14424193 | 0.92 | HSD17B10 (0.42) | HSD17B10GAAJAK2GRIA2ALDH1A1 | |
| SCHEMBL14424644 | 0.89 | NAMPT (0.49) | HSD17B10JAK2ALDH1A1HPGDMGLL | |
| SCHEMBL10114882 | 0.89 | NAMPT (0.49) | HSD17B10JAK2ALDH1A1HPGDMGLL | |
| SCHEMBL13204379 | 0.89 | NAMPT (0.49) | HSD17B10JAK2ALDH1A1HPGDMGLL | |
| SCHEMBL10133501 | 0.89 | NAMPT (0.49) | HSD17B10JAK2ALDH1A1HPGDMGLL | |
| SCHEMBL10133441 | 0.87 | HSD17B10 (0.51) | HSD17B10GAAJAK2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8115027-B2 | NPY Y5 antagonist | SHIONOGI & CO., LTD. (JP) | 2012-02-14 | — | — | US | disclosed |
| US-20100292500-A1 | NPY Y5 ANTAGONIST | KAWANISHI YASUYUKI | 2010-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100292500-A1 | NPY Y5 ANTAGONIST | NPY5R, NPY1R, NPY2R | HSD17B10 1102/4885GAA 3316/4885JAK2 1066/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.