Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 6/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.48 |
| ▸ | RELA | Q04206 | 3/20 | 0.47 |
| ▸ | MMP1 | P03956 | 2/20 | 0.45 |
| ▸ | MMP2 | P08253 | 2/20 | 0.45 |
| ▸ | MMP9 | P14780 | 2/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | G6PD | P11413 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12700847 | 0.88 | HPGD (0.68) | NFE2L2HPGDPTGS2RELAMMP1 | |
| SCHEMBL10128973 | 0.88 | HPGD (0.68) | NFE2L2HPGDPTGS2RELAMMP1 | |
| SCHEMBL8507374 | 0.88 | MMP1 (0.61) | NFE2L2PTGS2RELAMMP1MMP2 | |
| SCHEMBL8507370 | 0.88 | MMP1 (0.61) | NFE2L2PTGS2RELAMMP1MMP2 | |
| SCHEMBL1224423 | 0.88 | HPGD (0.58) | NFE2L2HPGDPTGS2RELAMMP1 | |
| SCHEMBL6292435 | 0.88 | HPGD (0.58) | NFE2L2HPGDPTGS2RELAMMP1 | |
| SCHEMBL10116485 | 0.88 | HPGD (0.58) | NFE2L2HPGDPTGS2RELAMMP1 | |
| SCHEMBL13989146 | 0.88 | HPGD (0.58) | NFE2L2HPGDPTGS2RELAMMP1 | |
| SCHEMBL1224421 | 0.88 | HPGD (0.58) | NFE2L2HPGDPTGS2RELAMMP1 | |
| SCHEMBL7607471 | 0.88 | HPGD (0.58) | NFE2L2HPGDPTGS2RELAMMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2146251-B1 | Electrophotographic photoconductor, image forming apparatus using the same, and process cartridge | RICOH CO LTD (JP) | 2012-02-08 | — | — | EP | disclosed |
| EP-2146251-A1 | Electrophotographic photoconductor, image forming apparatus using the same, and process cartridge | Ricoh Company, Ltd. (JP) | 2010-01-20 | — | — | EP | disclosed |