MMP1 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL24550	1.00	20/20
SCHEMBL24724	1.00	20/20
SCHEMBL25304	1.00	20/20
SCHEMBL25363	1.00	20/20
SCHEMBL25833	1.00	20/20
SCHEMBL26484	1.00	20/20
SCHEMBL26434	0.83	20/20
SCHEMBL25908	0.56	19/20
SCHEMBL25364	0.52	18/20
SCHEMBL26986	1.00	17/20
SCHEMBL25130	0.96	17/20
Betamethasone Benzoate (SCHEMBL49469)	0.76	17/20
SCHEMBL7812	0.73	17/20
SCHEMBL7547	0.83	16/20
SCHEMBL25832	0.57	16/20
Batimastat (SCHEMBL4332)	1.00	14/20
Batimastat (SCHEMBL4333)	1.00	14/20
SCHEMBL73249	0.76	11/20
Betamethasone Valerate (SCHEMBL7270)	0.81	10/20
SCHEMBL93888	0.79	10/20

Clinical trials — most relevant to MMP1 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Estimation of MMP-8 Levels in GCF and Serum and Its Correlation With Wound Healing and Clinical Outcomes After Coronally Advanced Flap and Subepithelial Connective Tissue Graft for Root Coverage in Recession Defects: A CLINICO-BIOCHEMICAL STUDY	PHASE4	SUSPENDED
Doxycycline In Lymphangioleiomyomatosis (LAM)	PHASE4	COMPLETED
Hyaluronic Acid vs Mitomycin-C in External Dacryocystorhinostomy	PHASE4	NOT_YET_RECRUITING
Comparing the Effects of Spironolactone With Chlortalidone on LV Mass in Patients With CKD	PHASE4	UNKNOWN
Tetracycline (Doxycycline) and Post Myocardial Infarction Remodeling	PHASE2	COMPLETED
Collagenase in the Treatment of Zone II Flexor Tendon Adhesions in the Hand	PHASE1/PHASE2	COMPLETED
Efficacy and Safety of Oltipraz in the Patients With Liver Fibrosis and Cirrhosis	PHASE2	COMPLETED
A Trial to Evaluate Efficacy and Safety of Buloxibutid in People With Idiopathic Pulmonary Fibrosis.	PHASE2	ACTIVE_NOT_RECRUITING
Synvisc to Treat Osteoarthritis of the Temporomandibular Joint	PHASE2	COMPLETED
Evaluation of Local Doxycycline in Smokers With Chronic Periodontitis	PHASE2	COMPLETED
Sputum Matrix Metalloproteinases (MMP) mRNA and Montelukast	PHASE2	COMPLETED
FS2 Safety and Tolerability Study in Healthy Volunteers	PHASE1	COMPLETED
A Phase I Study of Oral COL-3 (NSC-683551), a Matrix Metalloproteinase Inhibitor, in Patients With Refractory Metastatic Cancer	PHASE1	COMPLETED
The Role of Matrix Metalloproteinases (MMPs) in Orthodontic Tooth Movement	PHASE1	COMPLETED
Re-evaluation of Some Old Rheumatoid Arthritis Therapy: A Randomized Controlled Trial	nan	COMPLETED
Periodontal Health in Post COVID-19 Patients	nan	UNKNOWN
MMP-9, TIMP-9 in Lung Imaging and Functional of COVID-19	nan	COMPLETED
Case-control Study on Matrix Metalloproteinase Levels in Tissue in Patients With Keloid Scar	nan	COMPLETED
Plasma and Scarring of Diabetic Ulcers	nan	COMPLETED
The Effect of Eplerenone and Atorvastatin on Markers of Collagen Turnover in Diastolic Heart Failure	nan	COMPLETED
Matrix Metalloproteinases 7 and 9 in Rheumatoid Arthritis Patients With Interstitial Lung Disease	nan	NOT_YET_RECRUITING
Influence of Statins in Artery Aneurysms	nan	UNKNOWN
Evaluation of the Effectiveness of Physical Exercise on Aerobic Capacity in Patients With Cardiovascular Disease	nan	RECRUITING
Matrix Metalloproteinases After Surgery and/or Radiofrequency Ablation in Patients With Liver Metastases From Colorectal Cancer	nan	COMPLETED
The Effect of Non-surgical Periodontal Therapy Plus Doxycycline on HbA1c in Patients With Type 2 Diabetes Mellitus	nan	COMPLETED
Apoptotic Changes in Gingiva Caused by Smoking	nan	COMPLETED
Pathology, Venous Disease, and Clinical Correlations	nan	UNKNOWN
To Study the Effects of Host Genetic Factors on Liver Cirrhosis and Hepatocellular Carcinoma (HCC)	nan	UNKNOWN
Mechanisms Underlying SGLT2i Kidney Effect in DKD Progression	nan	NOT_YET_RECRUITING
Characterizing the Inflammation Around Dental Implants: Bacterial Infection, Hypersensitivity or Both?	nan	RECRUITING

Related proteins — ESM-2 sequence neighbours (a MMP1 binder may also engage these)

Protein	Name	Similarity
Q9XSZ5	—	1.000	Q9XSZ5 →
O70138	—	1.000	O70138 →
O88766	—	1.000	O88766 →
MMP8	Neutrophil collagenase	1.000	landscape →
Q28397	—	1.000	Q28397 →
Q63341	—	1.000	Q63341 →
P03957	—	0.999	P03957 →
P21692	—	0.998	P21692 →
P79287	—	0.998	P79287 →
P57748	—	0.998	P57748 →
P28053	—	0.997	P28053 →
Q9EPL5	—	0.997	Q9EPL5 →
P13943	—	0.996	P13943 →
MMP2	72 kDa type IV collagenase	0.996	landscape →
P07152	—	0.996	P07152 →
O18927	—	0.996	O18927 →
O77656	—	0.996	O77656 →
MMP3	Stromelysin-1	0.996	landscape →
Q9XT90	—	0.995	Q9XT90 →
O55123	—	0.995	O55123 →
O18767	—	0.995	O18767 →
Q9WTR0	—	0.995	Q9WTR0 →
Q6Y4Q5	—	0.995	Q6Y4Q5 →
Q10835	—	0.994	Q10835 →
Q90611	—	0.994	Q90611 →
MMP7	Matrilysin	0.994	landscape →
Q11005	—	0.994	Q11005 →
P50280	—	0.994	P50280 →
P79227	—	0.994	P79227 →
P53690	—	0.993	P53690 →