SCHEMBL10117140

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10116797	0.97	P2RX3 (0.52)	P2RX3MEN1KMT2ALMNAKDM4E
	SCHEMBL10116812	0.94	P2RX3 (0.58)	P2RX3MEN1KMT2ALMNAKDM4E
	SCHEMBL15139582	0.92	P2RX3 (0.55)	P2RX3MEN1KMT2ALMNAKDM4E
	SCHEMBL10116778	0.90	P2RX3 (0.55)	P2RX3MEN1KMT2ALMNAKDM4E
	SCHEMBL10116756	0.89	P2RX3 (0.61)	P2RX3MEN1KMT2AALDH1A1USP2
	SCHEMBL10117117	0.89	P2RX3 (0.61)	P2RX3MEN1KMT2AALDH1A1USP2
	SCHEMBL10116698	0.89	P2RX3 (0.62)	P2RX3MEN1KMT2ALMNAKDM4E
	SCHEMBL15139586	0.89	P2RX3 (0.54)	P2RX3MEN1KMT2ALMNAKDM4E
	SCHEMBL10116758	0.88	P2RX3 (0.52)	P2RX3MEN1KMT2ALMNAKDM4E
	SCHEMBL13521325	0.88	P2RX3 (0.53)	P2RX3MEN1KMT2ALMNAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.