Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.37 |
| ▸ | TSHR | P16473 | 6/20 | 0.37 |
| ▸ | LMNA | P02545 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10117388 | 0.90 | ALDH1A1 (0.39) | ALDH1A1TSHRLMNAMEN1KMT2A | |
| SCHEMBL10117352 | 0.88 | ALDH1A1 (0.41) | ALDH1A1TSHRLMNAMEN1KMT2A | |
| SCHEMBL13160799 | 0.83 | KMT2A (0.43) | ALDH1A1TSHRLMNAMEN1KMT2A | |
| SCHEMBL831054 | 0.83 | ALDH1A1 (0.41) | ALDH1A1TSHRLMNAMEN1KMT2A | |
| SCHEMBL10117561 | 0.83 | ALDH1A1 (0.41) | ALDH1A1TSHRLMNAMEN1KMT2A | |
| SCHEMBL2450771 | 0.83 | ALDH1A1 (0.41) | ALDH1A1TSHRLMNAMEN1KMT2A | |
| SCHEMBL2450772 | 0.83 | ALDH1A1 (0.41) | ALDH1A1TSHRLMNAMEN1KMT2A | |
| SCHEMBL205382 | 0.83 | ALDH1A1 (0.41) | ALDH1A1TSHRLMNAMEN1KMT2A | |
| SCHEMBL9281762 | 0.82 | ALDH1A1 (0.41) | ALDH1A1TSHRLMNAMEN1KMT2A | |
| SCHEMBL932279 | 0.82 | ALDH1A1 (0.41) | ALDH1A1TSHRLMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087976-A2 | NOVEL INHIBITORS OF HEPATITIS C VIRUS REPLICATION | INTERMUNE, INC. (US) | 2012-06-28 | — | — | WO | disclosed |