Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.70 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.68 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.68 |
| ▸ | HPGD | P15428 | 3/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.68 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.67 |
| ▸ | FAAH | O00519 | 1/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | BLM | P54132 | 2/20 | 0.66 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.66 |
| ▸ | NPC1 | O15118 | 1/20 | 0.66 |
| ▸ | GMNN | O75496 | 1/20 | 0.66 |
| ▸ | USP2 | O75604 | 1/20 | 0.66 |
| ▸ | TP53 | P04637 | 1/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.66 |
| ▸ | POLB | P06746 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22212823 | 0.95 | MAPT (0.74) | MAPTTRPV1ALOX12HPGDMEN1 | |
| SCHEMBL109158 | 0.85 | MAPT (0.73) | MAPTTRPV1ALOX12HPGDMEN1 | |
| SCHEMBL107219 | 0.84 | MAPT (0.71) | MAPTTRPV1ALOX12HPGDMEN1 | |
| SCHEMBL23417638 | 0.83 | MAPT (0.75) | MAPTTRPV1ALOX12HPGDMEN1 | |
| SCHEMBL18273974 | 0.83 | TRPV1 (0.75) | MAPTTRPV1ALOX12HPGDMEN1 | |
| SCHEMBL24649660 | 0.83 | MAPT (0.71) | MAPTTRPV1ALOX12HPGDMEN1 | |
| SCHEMBL14161593 | 0.83 | MAPT (0.72) | MAPTTRPV1ALOX12HPGDMEN1 | |
| SCHEMBL12953572 | 0.82 | TRPV1 (0.70) | MAPTTRPV1ALOX12HPGDMEN1 | |
| SCHEMBL14864042 | 0.82 | MAPT (1.00) | MAPTTRPV1ALOX12HPGDMEN1 | |
| SCHEMBL13151522 | 0.82 | MAPT (1.00) | MAPTTRPV1ALOX12HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8119742-B2 | Multi-armed catechol compound blends | KNC NER ACQUISITION SUB, INC. (US) | 2012-02-21 | — | — | US | disclosed |
| US-20100113828-A1 | MULTI-ARMED CATECHOL COMPOUND BLENDS | NERITES CORPORATION (US) | 2010-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100113828-A1 | MULTI-ARMED CATECHOL COMPOUND BLENDS | COMT, HAAO, PNMT | MAPT 909/4885TRPV1 609/4885ALOX12 50/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.