Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.39 |
| ▸ | GAA | P10253 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.38 |
| ▸ | CDK2 | P24941 | 2/20 | 0.38 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 6/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15170343 | 0.93 | CCNA2 (0.44) | KDM4EALDH1A1GAAKMT2APOLB | |
| SCHEMBL10119019 | 0.93 | CCNA2 (0.44) | KDM4EALDH1A1GAAKMT2APOLB | |
| SCHEMBL15169763 | 0.82 | SMN1; SMN2 (0.42) | SMN1; SMN2 | |
| SCHEMBL15169765 | 0.82 | SMN1; SMN2 (0.42) | SMN1; SMN2 | |
| SCHEMBL10119233 | 0.82 | TP53 (0.30) | ALDH1A1POLB | |
| SCHEMBL10119018 | 0.79 | TP53 (0.35) | ALDH1A1 | |
| SCHEMBL14004445 | 0.78 | KDM4E (0.30) | KDM4EALDH1A1 | |
| SCHEMBL14004448 | 0.78 | KDM4E (0.30) | KDM4EALDH1A1 | |
| SCHEMBL13904473 | 0.77 | ADORA2A (0.40) | KDM4EALDH1A1GAAKMT2ALMNA | |
| SCHEMBL19980890 | 0.74 | TP53 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2601268-B1 | PARTICLES FOR ELECTROPHORETIC DISPLAYS | MERCK PATENT GMBH (DE) | 2018-03-21 | — | — | EP | disclosed |
| US-9487611-B2 | Particles for electrophoretic displays | MERCK PATENT GMBH (DE) | 2016-11-08 | — | — | US | disclosed |
| US-20130208344-A1 | PARTICLES FOR ELECTROPHORETIC DISPLAYS | MERCK PATENT GMBH (DE) | 2013-08-15 | — | — | US | disclosed |
| WO-2012019704-A1 | PARTICLES FOR ELECTROPHORETIC DISPLAYS | MERCK PATENT GMBH (DE) | 2012-02-16 | — | — | WO | disclosed |