SCHEMBL10119018

SCHEMBL10119018

C=C(C)C(=O)OCCNc1nc(NCCOC(=O)C(=C)C)c(/N=N/c2sc(C#N)c(C)c2C#N)c(C)c1C#N

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ TP53 P04637 1/20 0.35
▸ THRB P10828 1/20 0.35
▸ ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10119233 0.95 TP53 (0.30) TP53THRBALDH1A1
SCHEMBL10119066 0.79 KDM4E (0.39) ALDH1A1
SCHEMBL19980841 0.77 CCNA2 (0.39) TP53THRBALDH1A1
SCHEMBL13904473 0.76 ADORA2A (0.40) ALDH1A1
SCHEMBL15169763 0.75 SMN1; SMN2 (0.42) —
SCHEMBL15169765 0.75 SMN1; SMN2 (0.42) —
SCHEMBL14004445 0.74 KDM4E (0.30) ALDH1A1
SCHEMBL19980892 0.73 CTSK (0.42) TP53THRBALDH1A1
SCHEMBL10119046 0.71 MAPT (0.32) —
SCHEMBL19980889 0.71 CCNA2 (0.38) TP53THRBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2785797-B1 PARTICLES FOR ELECTROPHORETIC DISPLAYS MERCK PATENT GMBH (DE) 2018-03-21 — — EP disclosed
EP-2601268-B1 PARTICLES FOR ELECTROPHORETIC DISPLAYS MERCK PATENT GMBH (DE) 2018-03-21 — — EP disclosed
US-9487611-B2 Particles for electrophoretic displays MERCK PATENT GMBH (DE) 2016-11-08 — — US disclosed
US-9383621-B2 Electrophoretic fluids MERCK PATENT GMBH (DE) 2016-07-05 — — US disclosed
US-9152006-B2 Particles for electrophoretic displays MERCK PATENT GMBH (DE) 2015-10-06 — — US disclosed
US-20150065644-A1 PARTICLES FOR ELECTROWETTING DISPLAYS MERCK PATENT GMBH (DE) 2015-03-05 — — US disclosed
US-20140320951-A1 PARTICLES FOR ELECTROPHORETIC DISPLAYS E INK CORPORATION 2014-10-30 — — US disclosed
US-20140313567-A1 ELECTROPHORETIC FLUIDS E INK CORPORATION 2014-10-23 — — US disclosed
WO-2013139427-A1 PARTICLES FOR ELECTROWETTING DISPLAYS MERCK PATENT GMBH (DE) 2013-09-26 — — WO disclosed
US-20130208344-A1 PARTICLES FOR ELECTROPHORETIC DISPLAYS MERCK PATENT GMBH (DE) 2013-08-15 — — US disclosed
WO-2013079158-A1 ELECTROPHORETIC FLUIDS MERCK PATENT GMBH (DE) 2013-06-06 — — WO disclosed
WO-2013079146-A1 PARTICLES FOR ELECTROPHORETIC DISPLAYS MERCK PATENT GMBH (DE) 2013-06-06 — — WO disclosed
WO-2012019704-A1 PARTICLES FOR ELECTROPHORETIC DISPLAYS MERCK PATENT GMBH (DE) 2012-02-16 — — WO disclosed
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