Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | ACE | P12821 | 1/20 | 0.56 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.53 |
| ▸ | CTSG | P08311 | 2/20 | 0.53 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.53 |
| ▸ | CMA1 | P23946 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.50 |
| ▸ | CTSL | P07711 | 3/20 | 0.49 |
| ▸ | CTSS | P25774 | 1/20 | 0.49 |
| ▸ | CTSK | P43235 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7318555 | 0.86 | PSMB5 (0.65) | ACEPSMB5CTSLCTSSCTSK | |
| SCHEMBL10119250 | 0.86 | PSMB5 (0.65) | ACEPSMB5CTSLCTSSCTSK | |
| SCHEMBL17326481 | 0.86 | HPGD (0.59) | HPGDKMT2AMEN1HTTSMN1; SMN2 | |
| SCHEMBL7278422 | 0.84 | HPGD (0.67) | HPGDKMT2AMEN1HTTSMN1; SMN2 | |
| SCHEMBL7278424 | 0.84 | HPGD (0.67) | HPGDKMT2AMEN1HTTSMN1; SMN2 | |
| SCHEMBL11125429 | 0.84 | HPGD (0.67) | HPGDKMT2AMEN1HTTSMN1; SMN2 | |
| SCHEMBL23013621 | 0.83 | ACE (0.59) | KMT2AMEN1ACETSHR | |
| SCHEMBL23013623 | 0.83 | ACE (0.59) | KMT2AMEN1ACETSHR | |
| SCHEMBL10118849 | 0.83 | HPGD (0.56) | HPGDKMT2AMEN1HTTSMN1; SMN2 | |
| SCHEMBL9829689 | 0.82 | CTSL (0.67) | ACEPSMB5CTSLCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012004554-A1 | ALDEHYDE COMPOUNDS AS INHIBITORS OF DUST MITE GROUP 1 PEPTIDASE ALLERGEN AND THEIR USE | ST GEORGE'S HOSPITAL MEDICAL SCHOOL (GB) | 2012-01-12 | — | — | WO | disclosed |