Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 2/20 | 0.60 |
| ▸ | CTSK | P43235 | 2/20 | 0.60 |
| ▸ | CTSB | P07858 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | MME | P08473 | 5/20 | 0.58 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.58 |
| ▸ | ANPEP | P15144 | 2/20 | 0.58 |
| ▸ | CTSL | P07711 | 3/20 | 0.57 |
| ▸ | ACE | P12821 | 1/20 | 0.56 |
| ▸ | CPA1 | P15085 | 1/20 | 0.56 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14297648 | 1.00 | CTSS (0.60) | CTSSCTSKCTSBL3MBTL1MME | |
| SCHEMBL10118946 | 0.95 | CTSS (0.67) | CTSSCTSKCTSBL3MBTL1MME | |
| SCHEMBL7318555 | 0.93 | PSMB5 (0.65) | CTSSCTSKCTSBL3MBTL1MME | |
| SCHEMBL10119250 | 0.93 | PSMB5 (0.65) | CTSSCTSKCTSBL3MBTL1MME | |
| SCHEMBL16375200 | 0.91 | MME (0.53) | CTSSCTSKCTSBL3MBTL1MME | |
| SCHEMBL10118961 | 0.90 | USP30 (0.56) | CTSSCTSKCTSBPSMB5CTSL | |
| SCHEMBL10119270 | 0.90 | PSMB5 (0.56) | CTSSCTSKCTSBPSMB5CTSL | |
| SCHEMBL7315389 | 0.88 | PSMB5 (0.60) | CTSSCTSKCTSBL3MBTL1MME | |
| SCHEMBL17994239 | 0.88 | MME (0.49) | CTSSCTSKCTSBL3MBTL1MME | |
| SCHEMBL12516880 | 0.87 | PSMB5 (0.56) | CTSSCTSKCTSBL3MBTL1PSMB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012004554-A1 | ALDEHYDE COMPOUNDS AS INHIBITORS OF DUST MITE GROUP 1 PEPTIDASE ALLERGEN AND THEIR USE | ST GEORGE'S HOSPITAL MEDICAL SCHOOL (GB) | 2012-01-12 | — | — | WO | disclosed |