Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PROKR2 | Q8NFJ6 | 5/20 | 0.63 |
| ▸ | GRN | P28799 | 1/20 | 0.40 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 7/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | MOGAT2 | Q3SYC2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10107420 | 1.00 | PROKR2 (0.63) | PROKR2GRNSORT1HTTPKM | |
| SCHEMBL3516927 | 0.89 | PROKR2 (0.57) | PROKR2GRNSORT1PKMKDM4E | |
| SCHEMBL565513 | 0.89 | PROKR2 (0.76) | PROKR2GRNSORT1HTTPKM | |
| SCHEMBL10107398 | 0.88 | PROKR2 (0.59) | PROKR2HTTPKMSMN1; SMN2KDM4E | |
| SCHEMBL564945 | 0.88 | PROKR2 (0.59) | PROKR2HTTPKMSMN1; SMN2KDM4E | |
| SCHEMBL15692849 | 0.87 | PROKR2 (0.59) | PROKR2HTTPKMSMN1; SMN2KDM4E | |
| SCHEMBL564820 | 0.87 | PROKR2 (0.59) | PROKR2HTTPKMSMN1; SMN2KDM4E | |
| SCHEMBL3518687 | 0.87 | PROKR2 (0.59) | PROKR2GRNSORT1HTTPKM | |
| SCHEMBL3518010 | 0.87 | PROKR2 (0.57) | PROKR2GRNSORT1PKMKDM4E | |
| SCHEMBL14515365 | 0.87 | PROKR2 (0.52) | PROKR2GRNSORT1HTTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120035149-A1 | Prokineticin Receptor Antagonists And Uses Thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120035149-A1 | Prokineticin Receptor Antagonists And Uses Thereof | PROKR2, PROKR1, GIPR | PROKR2 1/4885GRN 548/4885SORT1 1202/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.