PROKR2 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL564621	0.81	5/20
SCHEMBL564897	0.78	5/20
SCHEMBL565368	0.78	5/20
SCHEMBL565832	0.78	5/20
SCHEMBL565393	0.78	5/20
SCHEMBL565726	0.78	5/20
SCHEMBL564405	0.78	5/20
SCHEMBL564196	0.77	5/20
SCHEMBL565095	0.77	5/20
SCHEMBL565605	0.77	5/20
SCHEMBL565513	0.76	5/20
SCHEMBL565351	0.76	5/20
SCHEMBL565632	0.76	5/20
SCHEMBL564281	0.76	5/20
SCHEMBL564206	0.75	5/20
SCHEMBL564802	0.75	5/20
SCHEMBL565012	0.75	5/20
SCHEMBL565706	0.75	5/20
SCHEMBL565721	0.75	5/20
SCHEMBL565844	0.75	5/20

Clinical trials — most relevant to PROKR2 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Impact of Pantoprazole on 24-H Glycemic Control and on Post-prandial Glucose Excursion in Patients With Type 2 Diabetes	PHASE3	UNKNOWN
The Efficacy and Safety of Inpegsomatropin Injection in Children With Short Stature Born Small for Gestational Age	PHASE3	RECRUITING
Setmelanotide in Pediatric Participants With Rare Genetic Diseases of Obesity	PHASE3	COMPLETED
Studying the Influence of LEAP2 on Integrated Endocrine Control of Eating During Semaglutide Treatment	PHASE1/PHASE2	RECRUITING
Effects of Exenatide on Hypothalamic Obesity	PHASE1/PHASE2	COMPLETED
The Effect of rs7903146 Genotype on Islet GLP-1 Production in Humans	PHASE2	NOT_YET_RECRUITING
The Role of Phosphodiesterase Inhibitors in Incretin Secretion	PHASE1	COMPLETED
Magnetic Resonance Imaging of Motility in Crohn's 1	nan	COMPLETED
Role of the Microbiota in Obesity: Effect After Bariatric Surgery	nan	COMPLETED
Magnetic Resonance Imaging of Motility in Crohn's 2	nan	COMPLETED
The Effect of GIP, GLP-1 and GLP-2 in Individuals With Genetically Altered Receptor Function	nan	COMPLETED
Biological Sample Repository for Gastrointestinal Disorders	nan	ACTIVE_NOT_RECRUITING
Nutritional Management of Acute and Chronic Enterocutaneous Fistulae	nan	UNKNOWN
Study of the Molecular Basis in the Pathophysiology of Food Intake and Growth in Children	nan	COMPLETED
Plastic Bronchitis and Protein Losing Enteropathy in Children With Single Ventricle Physiology	nan	COMPLETED
Circular RNA and Chemerin in Breast Cancer Patient	nan	UNKNOWN
Dietary Carbohydrate and GERD in Veterans	nan	COMPLETED
Facilitated Release of Endogenous Enterokines	nan	COMPLETED
The Lean Living Study	nan	COMPLETED
Pre- and Post-prandial Levels of Appetite Regulatory Hormones in Adults	nan	COMPLETED
Endoscopic Gastric Reduction of Gastric Mucosa in Obesity	nan	UNKNOWN
Evaluation of Amino Acids Bioavailability in a Food Product Based on a Vegetable Protein Combination	nan	COMPLETED
Renin and Prorenin in Pregnancy	nan	COMPLETED
Eating Behaviour in Crohn's Disease	nan	COMPLETED
Calorie Restriction in Multiple Sclerosis	nan	ACTIVE_NOT_RECRUITING
EPICO: (Study for the Pro-resolution of Chronic Inflammation in Obesity. Original Acronym From Spanish)	nan	UNKNOWN
Brown Seaweed Extract on Glycemic Control and Body Weight	nan	COMPLETED
Peanut Consumption on Cognitive, Weight, and Inflammation	nan	RECRUITING
Sequencing of 14 Genes From Leptin Melanocortin Pathway in Severe Obesity in Childhood.	nan	UNKNOWN
Blocking of the Gut Hormone Receptor for Glucagon-like Peptide 2 (GLP-2) by the GLP-2 Receptor Antagonist GLP-2(3-33)	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a PROKR2 binder may also engage these)

Protein	Name	Similarity
Q8SPN1	—	1.000	Q8SPN1 →
Q8K458	—	1.000	Q8K458 →
Q8SPN2	—	1.000	Q8SPN2 →
PROKR1	Prokineticin receptor 1	1.000	landscape →
Q9JKL1	—	0.999	Q9JKL1 →
Q8R415	—	0.998	Q8R415 →
Q8R416	—	0.994	Q8R416 →
HCRTR2	Orexin receptor type 2	0.981	landscape →
Q5IS62	—	0.980	Q5IS62 →
Q9DDN6	—	0.980	Q9DDN6 →
O62809	—	0.980	O62809 →
Q9Z2D5	—	0.979	Q9Z2D5 →
Q9TUP7	—	0.978	Q9TUP7 →
Q9EQD2	—	0.978	Q9EQD2 →
Q924H0	—	0.978	Q924H0 →
O02836	—	0.978	O02836 →
P58308	—	0.976	P58308 →
NPY2R	Neuropeptide Y receptor type 2	0.976	landscape →
Q6VZZ7	—	0.974	Q6VZZ7 →
Q9NYM4	—	0.973	Q9NYM4 →
P90745	—	0.973	P90745 →
Q8WPA2	—	0.973	Q8WPA2 →
P97295	—	0.973	P97295 →
Q9GK74	—	0.972	Q9GK74 →
P79945	—	0.971	P79945 →
P34311	—	0.971	P34311 →
BRS3	Bombesin receptor subtype-3	0.971	landscape →
P79113	—	0.971	P79113 →
Q9VNM1	—	0.970	Q9VNM1 →
Q9Y5Y3	—	0.970	Q9Y5Y3 →