⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1107281 | 0.64 | — | — | |
| SCHEMBL4763204 | 0.62 | — | — | |
| SCHEMBL24667598 | 0.62 | — | — | |
| SCHEMBL21418617 | 0.58 | MEN1 (0.31) | — | |
| SCHEMBL14684695 | 0.57 | — | — | |
| SCHEMBL1107284 | 0.56 | — | — | |
| SCHEMBL793375 | 0.55 | — | — | |
| SCHEMBL23599397 | 0.54 | RAD52 (0.33) | — | |
| SCHEMBL19026970 | 0.54 | ALDH1A1 (0.31) | — | |
| SCHEMBL19102833 | 0.54 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170071964-A1 | METHODS FOR TREATING ARENAVIRIDAE AND CORONAVIRIDAE VIRUS INFECTIONS | GILEAD SCIENCES, INC. | 2017-03-16 | — | — | US | disclosed |
| US-20120027752-A1 | METHODS AND COMPOUNDS FOR TREATING PARAMYXOVIRIDAE VIRUS INFECTIONS | GILEAD SCIENCES, INC. (US) | 2012-02-02 | — | — | US | disclosed |