Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 7/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.45 |
| ▸ | CASP1 | P29466 | 3/20 | 0.45 |
| ▸ | CASP7 | P55210 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 3/20 | 0.40 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 2/20 | 0.38 |
| ▸ | ETV6 | P41212 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15179450 | 0.95 | GAA (0.44) | GAAKDM4ECASP1CASP7ALDH1A1 | |
| SCHEMBL10120304 | 0.92 | KDM4E (0.45) | GAAKDM4ECASP1CASP7ALDH1A1 | |
| SCHEMBL10120316 | 0.88 | KDM4E (0.46) | GAAKDM4ECASP1CASP7ALDH1A1 | |
| SCHEMBL10120111 | 0.88 | KDM4E (0.45) | GAAKDM4ECASP1CASP7ALDH1A1 | |
| SCHEMBL15179409 | 0.86 | CNR2 (0.42) | GAAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL10120107 | 0.86 | KDM4E (0.44) | GAAKDM4ECASP1CASP7ALDH1A1 | |
| SCHEMBL10120099 | 0.85 | ALOX5 (0.43) | GAAMAPTTP53ALOX5BRD4 | |
| SCHEMBL15179298 | 0.83 | GAA (0.48) | GAAKDM4ECASP1CASP7ALDH1A1 | |
| SCHEMBL10120106 | 0.82 | CNR2 (0.43) | GAAKDM4EALDH1A1MAPTRAB9A | |
| SCHEMBL15179269 | 0.82 | GAA (0.47) | GAAKDM4ECASP1CASP7ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012018662-A2 | FUSED-IMIDAZOYL COMPOUNDS USEFUL AS ANTIMICROBIAL AGENTS | SCHERING CORPORATION (US) | 2012-02-09 | — | — | WO | disclosed |