Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 14/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
| ▸ | CASP1 | P29466 | 3/20 | 0.43 |
| ▸ | CASP7 | P55210 | 3/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 2/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 9/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10120302 | 0.96 | GAA (0.43) | GAAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL15179323 | 0.88 | GRM5 (0.42) | GAAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL10120627 | 0.83 | GAA (0.45) | GAAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL10120102 | 0.83 | GAA (0.44) | GAAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL10120303 | 0.81 | GAA (0.45) | GAAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL10120195 | 0.79 | KDM4E (0.46) | GAAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL15179381 | 0.79 | GAA (0.45) | GAAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL10120304 | 0.79 | KDM4E (0.45) | GAAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL15179285 | 0.78 | GAA (0.46) | GAAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL14963797 | 0.78 | GAA (0.57) | GAAKDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012018662-A2 | FUSED-IMIDAZOYL COMPOUNDS USEFUL AS ANTIMICROBIAL AGENTS | SCHERING CORPORATION (US) | 2012-02-09 | — | — | WO | disclosed |