Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY1 | P47900 | 10/20 | 0.56 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 8/20 | 0.51 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.51 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.51 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.51 |
| ▸ | P2RY11 | Q96G91 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12269837 | 0.92 | P2RY1 (0.55) | P2RY1P2RY2ADORA3ADORA1ADORA2A | |
| SCHEMBL10121164 | 0.87 | P2RY1 (0.73) | P2RY1P2RY2ADORA3ADORA1ADORA2A | |
| SCHEMBL10121327 | 0.87 | ADORA3 (0.67) | P2RY1P2RY2ADORA3ADORA1ADORA2A | |
| SCHEMBL12269798 | 0.80 | P2RY1 (0.58) | P2RY1P2RY2ADORA3ADORA1ADORA2A | |
| SCHEMBL10121166 | 0.80 | P2RY1 (0.73) | P2RY1P2RY2ADORA3ADORA1ADORA2A | |
| SCHEMBL17830413 | 0.79 | P2RY1 (0.72) | P2RY1P2RY2ADORA3ADORA1ADORA2A | |
| SCHEMBL12269667 | 0.79 | ADORA3 (0.66) | P2RY1P2RY2ADORA3ADORA1ADORA2A | |
| SCHEMBL12269878 | 0.77 | P2RY1 (0.61) | P2RY1P2RY2ADORA3ADORA1ADORA2A | |
| SCHEMBL12269827 | 0.77 | P2RY1 (0.40) | P2RY1P2RY2ADORA3ADORA1ADORA2A | |
| SCHEMBL17830427 | 0.77 | P2RY1 (0.40) | P2RY1P2RY2ADORA3ADORA1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9303053-B2 | Compositions and methods to treat cardiac diseases | UNIVERSITY OF CONNECTICUT (US) | 2016-04-05 | — | — | US | disclosed |
| US-20150038463-A1 | COMPOSITIONS AND METHODS TO TREAT CARDIAC DISEASES | UNIV CONNECTICUT (US) | 2015-02-05 | — | — | US | disclosed |
| WO-2011103552-A9 | AMP DERIVATIVES FOR TREATING CARDIAC DISEASES | UNIVERSITY OF CONNECTICUT (US) | 2012-04-26 | — | — | WO | disclosed |
| WO-2011103552-A2 | COMPOSITIONS AND METHODS TO TREAT CARDIAC DISEASES | UNIVERSITY OF CONNECTICUT (US) | 2011-08-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150038463-A1 | COMPOSITIONS AND METHODS TO TREAT CARDIAC DISEASES | P2RY12, P2RX6, P2RY14 | P2RY1 4/4885P2RY2 8/4885ADORA3 84/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.