Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 4/20 | 0.53 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.46 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.46 |
| ▸ | PTGER4 | P35408 | 5/20 | 0.45 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.43 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12239078 | 0.91 | BDKRB1 (0.54) | BDKRB1CARM1PRMT6MAPK14CYP3A4 | |
| SCHEMBL765565 | 0.90 | BDKRB1 (0.56) | BDKRB1MAPK14CYP3A4LIPGL3MBTL1 | |
| SCHEMBL764495 | 0.89 | BDKRB1 (0.51) | BDKRB1CARM1PRMT6PTGER4PTGER2 | |
| SCHEMBL765831 | 0.89 | BDKRB1 (0.51) | BDKRB1PTGER4PTGER2MAPK14CXCR4 | |
| SCHEMBL765204 | 0.89 | BDKRB1 (0.51) | BDKRB1CARM1PRMT6PTGER4PTGER2 | |
| SCHEMBL765842 | 0.89 | BDKRB1 (0.53) | BDKRB1CARM1PRMT6PTGER4MAPK14 | |
| SCHEMBL765546 | 0.89 | BDKRB1 (0.53) | BDKRB1CARM1PRMT6PTGER4PTGER2 | |
| SCHEMBL764461 | 0.89 | BDKRB1 (0.61) | BDKRB1MAPK14CYP3A4CNR1 | |
| SCHEMBL10121362 | 0.88 | BDKRB1 (0.58) | BDKRB1PTGER4PTGER2MAPK14CXCR4 | |
| SCHEMBL12239059 | 0.87 | BDKRB1 (0.53) | BDKRB1PTGER4PTGER2MAPK14CXCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2188254-B1 | NOVEL BRADYKININ B1-ANTAGONISTS | BOEHRINGER INGELHEIM INT (DE) | 2012-03-21 | — | — | EP | disclosed |