Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 4/20 | 0.51 |
| ▸ | PTGER4 | P35408 | 5/20 | 0.45 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.45 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | METAP2 | P50579 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.36 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10121385 | 0.89 | BDKRB1 (0.53) | BDKRB1PTGER4PTGER2CXCR4MAPK14 | |
| SCHEMBL765831 | 0.89 | BDKRB1 (0.51) | BDKRB1PTGER4PTGER2CXCR4MAPK14 | |
| SCHEMBL764495 | 0.89 | BDKRB1 (0.51) | BDKRB1PTGER4PTGER2CXCR4MAPK14 | |
| SCHEMBL764493 | 0.89 | BDKRB1 (0.51) | BDKRB1PTGER4PTGER2MAPK14CYP3A4 | |
| SCHEMBL10121362 | 0.88 | BDKRB1 (0.58) | BDKRB1PTGER4PTGER2CXCR4MAPK14 | |
| SCHEMBL764449 | 0.87 | BDKRB1 (0.49) | BDKRB1PTGER4PTGER2CXCR4MAPK14 | |
| SCHEMBL765639 | 0.86 | BDKRB1 (0.50) | BDKRB1PTGER4PTGER2MAPK14CYP3A4 | |
| SCHEMBL764429 | 0.85 | BDKRB1 (0.58) | BDKRB1PTGER4PTGER2CXCR4MAPK14 | |
| SCHEMBL10121359 | 0.84 | BDKRB1 (0.55) | BDKRB1PTGER4PTGER2CXCR4MAPK14 | |
| SCHEMBL13904099 | 0.84 | BDKRB1 (0.51) | BDKRB1PTGER4PTGER2CXCR4MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2188254-B1 | NOVEL BRADYKININ B1-ANTAGONISTS | BOEHRINGER INGELHEIM INT (DE) | 2012-03-21 | — | — | EP | disclosed |