Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 3/20 | 0.44 |
| ▸ | ESR1 | P03372 | 9/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 9/20 | 0.34 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.32 |
| ▸ | SNCA | P37840 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | ACP1 | P24666 | 1/20 | 0.31 |
| ▸ | STS | P08842 | 1/20 | 0.31 |
| ▸ | NQO1 | P15559 | 1/20 | 0.31 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1104938 | 0.77 | APP (0.44) | APPESR1ESR2SNCASTS | |
| SCHEMBL13212103 | 0.70 | APP (0.57) | APPESR1ESR2SNCAAKR1B1 | |
| SCHEMBL15887430 | 0.69 | APP (0.56) | APPESR1ESR2SNCASTS | |
| SCHEMBL10205581 | 0.68 | APP (0.55) | APPESR1ESR2SNCAAKR1B1 | |
| SCHEMBL12714431 | 0.65 | ESR1 (0.40) | APPESR1ESR2SNCA | |
| SCHEMBL10123100 | 0.63 | MEN1 (0.38) | APPCYP1A2 | |
| SCHEMBL10264705 | 0.62 | APP (0.44) | APPESR1ESR2SNCAAKR1B1 | |
| SCHEMBL8066 | 0.62 | APP (1.00) | APPESR1ESR2SNCACYP1A2 | |
| SCHEMBL1104939 | 0.62 | APP (0.46) | APPESR1ESR2STSCYP1A2 | |
| SCHEMBL25232227 | 0.62 | APP (0.46) | APPESR1ESR2SNCACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9846168-B2 | Fluorescent metal ion indicators with large stokes shifts | Life Technologies Corporation (US) | 2017-12-19 | — | — | US | disclosed |
| US-20160305964-A1 | Fluorescent Metal Ion Indicators with Large Stokes Shifts | MOLECULAR PROBES, INC. | 2016-10-20 | — | — | US | disclosed |
| US-9372181-B2 | Fluorescent metal ion indicators with large stokes shifts | Life Technologies Corporation (US) | 2016-06-21 | — | — | US | disclosed |
| US-20140363824-A1 | Fluorescent Metal Ion Indicators with Large Stokes Shifts | MOLECULAR PROBES, INC. | 2014-12-11 | — | — | US | disclosed |
| US-8785208-B2 | Fluorescent metal ion indicators with large stokes shifts | Life Technologies Corporation (US) | 2014-07-22 | — | — | US | disclosed |
| US-20120009683-A1 | Fluorescent Metal Ion Indicators with Large Stokes Shifts | Life Technologies Corporation (US) | 2012-01-12 | — | — | US | disclosed |
| US-20090029389-A1 | FLUORESCENT METAL ION INDICATORS WITH LARGE STOKES SHIFTS | INVITROGEN CORPORATION (US) | 2009-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120009683-A1 | Fluorescent Metal Ion Indicators with Large Stokes Shifts | SARAF, STIM1, ORAI1 | APP 1748/4885ESR1 367/4885ESR2 1478/4885 |
| US-20160305964-A1 | Fluorescent Metal Ion Indicators with Large Stokes Shifts | SARAF, STIM1, ORAI1 | APP 1748/4885ESR1 367/4885ESR2 1478/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.