Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 7/20 | 0.33 |
| ▸ | SCP2 | P22307 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.30 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30898571 | 0.78 | RAB9A (0.46) | MEN1NPC1POLBRAB9AKMT2A | |
| SCHEMBL27310713 | 0.78 | RAB9A (0.46) | MEN1NPC1POLBRAB9AKMT2A | |
| SCHEMBL15887423 | 0.71 | MEN1 (0.45) | MEN1NPC1POLBRAB9AKMT2A | |
| SCHEMBL1104939 | 0.67 | APP (0.46) | MEN1NPC1POLBRAB9AKMT2A | |
| SCHEMBL3494330 | 0.66 | APP (0.63) | MEN1NPC1POLBRAB9AKMT2A | |
| SCHEMBL8858355 | 0.64 | NPC1 (0.76) | MEN1NPC1POLBRAB9AKMT2A | |
| SCHEMBL13965008 | 0.64 | MEN1 (0.37) | MEN1NPC1POLBRAB9AKMT2A | |
| SCHEMBL10123098 | 0.63 | APP (0.44) | APPCYP1A2 | |
| SCHEMBL13521801 | 0.61 | SCP2 (0.67) | MEN1NPC1POLBRAB9AKMT2A | |
| SCHEMBL5916788 | 0.60 | MEN1 (0.50) | MEN1NPC1POLBRAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9846168-B2 | Fluorescent metal ion indicators with large stokes shifts | Life Technologies Corporation (US) | 2017-12-19 | — | — | US | disclosed |
| US-20160305964-A1 | Fluorescent Metal Ion Indicators with Large Stokes Shifts | MOLECULAR PROBES, INC. | 2016-10-20 | — | — | US | disclosed |
| US-9372181-B2 | Fluorescent metal ion indicators with large stokes shifts | Life Technologies Corporation (US) | 2016-06-21 | — | — | US | disclosed |
| US-20140363824-A1 | Fluorescent Metal Ion Indicators with Large Stokes Shifts | MOLECULAR PROBES, INC. | 2014-12-11 | — | — | US | disclosed |
| US-8785208-B2 | Fluorescent metal ion indicators with large stokes shifts | Life Technologies Corporation (US) | 2014-07-22 | — | — | US | disclosed |
| US-20120009683-A1 | Fluorescent Metal Ion Indicators with Large Stokes Shifts | Life Technologies Corporation (US) | 2012-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120009683-A1 | Fluorescent Metal Ion Indicators with Large Stokes Shifts | SARAF, STIM1, ORAI1 | MEN1 137/4885NPC1 968/4885POLB 4846/4885 |
| US-20160305964-A1 | Fluorescent Metal Ion Indicators with Large Stokes Shifts | SARAF, STIM1, ORAI1 | MEN1 137/4885NPC1 968/4885POLB 4846/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.