Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | CRHBP | P24387 | 1/20 | 0.52 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HTR6 | P50406 | 7/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10123314 | 0.92 | KMT2A (0.56) | THRBALDH1A1CRHBPCRHR2TP53 | |
| SCHEMBL10123256 | 0.85 | THRB (0.64) | THRBALDH1A1HPGDCRHBPCRHR2 | |
| SCHEMBL10123313 | 0.84 | THRB (0.63) | THRBALDH1A1HPGDTP53MAPT | |
| SCHEMBL10123316 | 0.84 | THRB (0.63) | THRBALDH1A1HPGDTP53MAPT | |
| SCHEMBL667284 | 0.84 | THRB (0.79) | THRBTP53MAPTHTR6POLB | |
| SCHEMBL8029045 | 0.83 | KDM4E (0.61) | THRBALDH1A1HPGDCRHBPCRHR2 | |
| SCHEMBL10123311 | 0.82 | THRB (0.61) | THRBALDH1A1HPGDTP53MAPT | |
| SCHEMBL10123317 | 0.82 | THRB (0.61) | THRBALDH1A1TP53MAPTHTR6 | |
| SCHEMBL13573198 | 0.81 | THRB (0.60) | THRBALDH1A1HPGDTP53MAPT | |
| SCHEMBL10123263 | 0.81 | THRB (0.58) | THRBALDH1A1HPGDTP53HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120046282-A1 | METHODS AND COMPOUNDS FOR ANTIMICROBIAL INTERVENTION | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2012-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046282-A1 | METHODS AND COMPOUNDS FOR ANTIMICROBIAL INTERVENTION | FDFT1, COASY, KAT5 | THRB 2096/4885ALDH1A1 4179/4885HPGD 1949/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.