SCHEMBL1012355

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL39883	0.93	GABRP (0.49)	ALOX5PTGS2KAT8PPARAPTGES
	SCHEMBL40166	0.86	PTPN1 (0.59)	ALOX5PTGS2PTPN1MCL1PTPN11
	SCHEMBL334415	0.86	KAT8 (0.50)	ALOX5PTGS2KAT8PPARABID
	SCHEMBL9303706	0.86	KAT8 (0.61)	ALOX5PTGS2KAT8PPARABID
	SCHEMBL7780121	0.86	KAT8 (0.61)	ALOX5PTGS2KAT8PPARABID
	SCHEMBL9955366	0.86	KAT8 (0.61)	ALOX5PTGS2KAT8PPARABID
	SCHEMBL9324615	0.86	KAT8 (0.50)	ALOX5PTGS2KAT8PPARABID
	SCHEMBL9500875	0.86	KAT8 (0.50)	ALOX5PTGS2KAT8PPARABID
	SCHEMBL7781047	0.86	KAT8 (0.50)	ALOX5PTGS2KAT8PPARABID
	SCHEMBL3220998	0.86	KAT8 (0.61)	ALOX5PTGS2KAT8PPARABID

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.