SCHEMBL1012418

SCHEMBL1012418

C=CCSC=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL345847 0.73
SCHEMBL10671663 0.72
SCHEMBL2838456 0.72
SCHEMBL6660314 0.72
SCHEMBL3257777 0.69
SCHEMBL5847156 0.67
SCHEMBL8958848 0.67 TRPA1 (0.44)
SCHEMBL251278 0.67
SCHEMBL170910 0.67
SCHEMBL9351601 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109415297-A New antibiotic 布洛斯 & 库珀制药私人有限公司 2019-03-01 CN claimed
CN-107922288-A SYNTHESIS OF ARYL COMPOUNDS 布洛斯 & 库珀制药私人有限公司 2018-04-17 CN claimed
CN-104588113-B Macromolecule load catalyst and its application in arenes selectivity chlorination reaction 东南大学 2017-08-04 CN claimed
CN-104588113-A Polymer supported catalyst and application thereof in aromatic selective chlorination reaction UNIV SOUTHEAST 2015-05-06 CN claimed
CN-103623867-A Composite catalyst for selective chlorination of aromatic compounds and application thereof UNIV SOUTHEAST 2014-03-12 CN claimed
CN-1193622-A Method for production of sulfide group-containing thiol compound NIPPON CATALYTIC CHEM IND (JP) 1998-09-23 CN claimed
CN-109415297-A New antibiotic 布洛斯 & 库珀制药私人有限公司 2019-03-01 CN disclosed
CN-107922288-A SYNTHESIS OF ARYL COMPOUNDS 布洛斯 & 库珀制药私人有限公司 2018-04-17 CN disclosed
CN-104588113-B Macromolecule load catalyst and its application in arenes selectivity chlorination reaction 东南大学 2017-08-04 CN disclosed
CN-104870515-B Sheet-like epoxy resin composition, method for producing organic EL device using same, organic EL device, and organic EL display panel 三井化学株式会社 2017-07-07 CN disclosed
CN-103636286-B Surface sealant for optical semiconductor, method for manufacturing organic EL device using same, organic EL device, and organic EL display panel 三井化学株式会社 2017-02-15 CN disclosed
US-9403756-B2 N-phenyl anthranilic acid derivatives and uses thereof RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2016-08-02 US disclosed
EP-2203411-B1 N-PHENYL ANTHRANILIC ACID DERIVATIVES AND USES THEREOF UNIV RAMOT (IL) 2016-01-06 EP disclosed
CN-1193622-A Method for production of sulfide group-containing thiol compound NIPPON CATALYTIC CHEM IND (JP) 1998-09-23 CN disclosed
CN-1040587-A Phenylalkylthiopheneand and related compound MERRELL DOW PHARMA (US) 1990-03-21 CN disclosed
EP-0096583-B1 5-AROYL-1,2-DIHYDRO-3H-PYRROLO 1,2-A PYRROLE-1-CARBOXYLIC ACIDS AND DERIVATIVES THEREOF, PROCESSES FOR THEIR PREPARATION, AND INTERMEDIATES THEREFOR SYNTEX (U.S.A.) INC. (US) 1987-09-09 EP disclosed
US-4612325-A 5-Aroyl-6-alkylthio-1,2-dihydro-3H-pyrrolo(1,2-A)pyrrole-1-carboxylic acids and use thereof as analgesics and anti-inflammatories SYNTEX (U.S.A) INC. (US) 1986-09-16 US disclosed
EP-0096583-A2 5-Aroyl-1,2-dihydro-3H-pyrrolo 1,2-a pyrrole-1-carboxylic acids and derivatives thereof, processes for their preparation, and intermediates therefor SYNTEX (U.S.A.) INC. (US) 1983-12-21 EP disclosed
US-4007211-A OXIDATIVE DECARBOXYLATION WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 1977-02-08 US disclosed
US-3932508-A Polyfluoromethylthio-substituted compounds MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1976-01-13 US disclosed