Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 9/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | SCP2 | P22307 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.35 |
| ▸ | MAPT | P10636 | 8/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.35 |
| ▸ | HTT | P42858 | 6/20 | 0.35 |
| ▸ | GLA | P06280 | 4/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | CASP1 | P29466 | 3/20 | 0.35 |
| ▸ | CASP7 | P55210 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12925210 | 1.00 | MEN1 (0.53) | MEN1KMT2ANPC1RAB9APOLB | |
| SCHEMBL995724 | 1.00 | MEN1 (0.53) | MEN1KMT2ANPC1RAB9APOLB | |
| SCHEMBL12950577 | 0.90 | MEN1 (0.52) | MEN1KMT2ANPC1RAB9APOLB | |
| SCHEMBL12925166 | 0.89 | MEN1 (0.64) | MEN1KMT2ANPC1RAB9APOLB | |
| SCHEMBL995698 | 0.89 | MEN1 (0.64) | MEN1KMT2ANPC1RAB9APOLB | |
| SCHEMBL31235518 | 0.89 | MEN1 (0.64) | MEN1KMT2ANPC1RAB9APOLB | |
| SCHEMBL995700 | 0.89 | MEN1 (0.64) | MEN1KMT2ANPC1RAB9APOLB | |
| SCHEMBL12925167 | 0.84 | MEN1 (0.56) | MEN1KMT2ANPC1RAB9APOLB | |
| SCHEMBL996947 | 0.84 | MEN1 (0.56) | MEN1KMT2ANPC1RAB9APOLB | |
| SCHEMBL996949 | 0.84 | MEN1 (0.56) | MEN1KMT2ANPC1RAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2269996-B1 | MEDICINAL COMPOSITION CONTAINING BENZO[A]PHENOXANTHIN COMPOUND AS THE ACTIVE INGREDIENT FOR PREVENTING OR TREATING PROTOZOAL DISEASE | HOSHI UNIVERSITY (JP) | 2012-10-17 | — | — | EP | disclosed |
| EP-2269996-A1 | MEDICINAL COMPOSITION CONTAINING BENZO[A]PHENOXANTHIN COMPOUND AS THE ACTIVE INGREDIENT FOR PREVENTING OR TREATING PROTOZOAL DISEASE | Hoshi University (JP) | 2011-01-05 | — | — | EP | disclosed |
| WO-2009113569-A1 | MEDICINAL COMPOSITION CONTAINING BENZO[A]PHENOXANTHIN COMPOUND AS THE ACTIVE INGREDIENT FOR PREVENTING OR TREATING PROTOZOAL DISEASE | 学校法人星薬科大学 (JP) | 2009-09-17 | — | — | WO | disclosed |