Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | GHSR | Q92847 | 2/20 | 0.31 |
| ▸ | CTSD | P07339 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6534360 | 1.00 | KDM4E (0.42) | KDM4ETSHRALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL6534568 | 1.00 | KDM4E (0.42) | KDM4ETSHRALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL6534640 | 1.00 | KDM4E (0.42) | KDM4ETSHRALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL6534361 | 1.00 | KDM4E (0.42) | KDM4ETSHRALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL6534645 | 1.00 | KDM4E (0.42) | KDM4ETSHRALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL6534635 | 1.00 | KDM4E (0.42) | KDM4ETSHRALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL16500668 | 0.82 | KDM4E (0.47) | KDM4EALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL29717170 | 0.82 | KDM4E (0.47) | KDM4EALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL6466586 | 0.82 | KDM4E (0.47) | KDM4EALDH1A1CYP3A4CYP2C9CYP2C19 | |
| Isoleucine SCHEMBL9839167 | 0.82 | KDM4E (0.38) | KDM4EALDH1A1CYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113735727-B | Preparation method of raceme ketoisoleucine calcium and intermediate thereof | 北京福元医药股份有限公司沧州分公司 | 2024-05-24 | — | — | CN | claimed |
| CN-109468304-B | Hydantoinase mutants | 赢创运营有限公司 | 2022-04-19 | — | — | CN | claimed |
| CN-113735727-A | Preparation method of racemic ketone isoleucine calcium and intermediate thereof | 北京福元医药股份有限公司沧州分公司 | 2021-12-03 | — | — | CN | claimed |
| CN-109468304-A | The mutant of Hydantoinase | 赢创工业化学有限公司 | 2019-03-15 | — | — | CN | claimed |
| US-9957536-B2 | Mutants of hydantoinase | EVONIK TECHNOCHEMIE GMBH (DE) | 2018-05-01 | — | — | US | claimed |
| EP-2780451-B1 | MUTANTS OF HYDANTOINASE | EVONIK TECHNOCHEMIE GMBH (DE) | 2017-09-20 | — | — | EP | claimed |
| US-20150056667-A1 | MUTANTS OF HYDANTOINASE | EVONIK OPERATIONS GMBH (DE) | 2015-02-26 | — | — | US | claimed |
| EP-2780451-A1 | MUTANTS OF HYDANTOINASE | Evonik Industries AG (DE) | 2014-09-24 | — | — | EP | claimed |
| WO-2013072486-A1 | MUTANTS OF HYDANTOINASE | EVONIK INDUSTRIES AG (DE) | 2013-05-23 | — | — | WO | claimed |
| US-20050202542-A1 | Production method of D-alloisoleucine | AJINOMOTO CO., INC. (JP) | 2005-09-15 | — | — | US | claimed |
| US-20050112729-A1 | Recombinant DNA having hydantoinase gene and carbamylase gene and process for producing amino acid | AJINOMOTO CO., INC. (JP) | 2005-05-26 | — | — | US | claimed |
| US-5071752-A | Contacting nocardia or its enzymes with a dl-imidazolidinedione derivative; immobilization | SCHERING AKTIENGESELLSCHAFT (DE) | 1991-12-10 | — | — | US | claimed |
| EP-4608574-A1 | PROCESSES FOR REDUCING ENVIRONMENTAL AVAILABILITY OF ENVIRONMENTAL POLLUTANTS | ALBEMARLE CORPORATION (US) | 2025-09-03 | — | — | EP | disclosed |
| CN-120202073-A | Method for reducing the environmental effectiveness of environmental pollutants | 雅宝公司 | 2025-06-24 | — | — | CN | disclosed |
| CN-119899102-A | Synthesis method of alpha-ketoisoleucine calcium intermediate and application of alpha-ketoisoleucine calcium intermediate in preparation of alpha-ketoisoleucine calcium | 河北天成药业股份有限公司 | 2025-04-29 | — | — | CN | disclosed |
| WO-2024177858-A1 | PROCESSES FOR REDUCING ENVIRONMENTAL AVAILABILITY OF ENVIRONMENTAL POLLUTANTS | ALBEMARLE CORPORATION (US) | 2024-08-29 | — | — | WO | disclosed |
| US-4331809-A | INTERMEDIATES FOR PREPARING POLYURETHANE FOAMS AND ELASTOMERS | BASF WYANDOTTE CORPORATION (US) | 1982-05-25 | — | — | US | disclosed |
| US-4331810-A | Carbamylbiuret-modified polyisocyanates | BASF WYANDOTTE CORPORATION (US) | 1982-05-25 | — | — | US | disclosed |
| US-4330636-A | Carbamylbiuret-modified polyisocyanates | BASF WYANDOTTE CORPORATION (US) | 1982-05-18 | — | — | US | disclosed |
| US-4271087-A | WHICH CAN ALSO CONTAIN GUANIDINE LINKAGES AND THIOUREA LINKAGES | BASF WYANDOTTE CORPORATION (US) | 1981-06-02 | — | — | US | disclosed |