Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | GHSR | Q92847 | 2/20 | 0.31 |
| ▸ | CTSD | P07339 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6534360 | 1.00 | KDM4E (0.42) | KDM4ETSHRALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL6534640 | 1.00 | KDM4E (0.42) | KDM4ETSHRALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL6534361 | 1.00 | KDM4E (0.42) | KDM4ETSHRALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL6534645 | 1.00 | KDM4E (0.42) | KDM4ETSHRALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL6534635 | 1.00 | KDM4E (0.42) | KDM4ETSHRALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL1012467 | 1.00 | KDM4E (0.42) | KDM4ETSHRALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL16500668 | 0.82 | KDM4E (0.47) | KDM4EALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL29717170 | 0.82 | KDM4E (0.47) | KDM4EALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL6466586 | 0.82 | KDM4E (0.47) | KDM4EALDH1A1CYP3A4CYP2C9CYP2C19 | |
| Isoleucine SCHEMBL9839167 | 0.82 | KDM4E (0.38) | KDM4EALDH1A1CYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6830904-B2 | Producing single diastereomers of isoleucine in high stereochemical purity by converting (R)-2-methylbutyraldehyde to a diastereomeric mixture of D-isoleucine hydantoin and L-allo-isoleucine hydantoin (5S-((R)-1-methylpropyl)hydantoin) | BIOCATALYTICS, INC. | 2004-12-14 | — | — | US | disclosed |
| US-20040048342-A1 | Methods for producing diastereomers of isoleucine | CODEXIS, INC. | 2004-03-11 | — | — | US | disclosed |