SCHEMBL10124865

SCHEMBL10124865

Bc1ccc(-c2cc3ccccc3c3ccccc23)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 1/20 0.50
ALDH1A1 P00352 4/20 0.46
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
HPGD P15428 2/20 0.46
KDM4E B2RXH2 2/20 0.46
MAPT P10636 2/20 0.46
MPI P34949 1/20 0.46
HSD17B10 Q99714 3/20 0.44
HIF1A Q16665 2/20 0.44
TSHR P16473 2/20 0.44
MAPK1 P28482 1/20 0.44
CASP1 P29466 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
TRPM4 Q8TD43 1/20 0.43
CYP1B1 Q16678 1/20 0.43
HPRT1 P00492 1/20 0.41
NISCH Q9Y2I1 1/20 0.40
GPR84 Q9NQS5 6/20 0.39
CYP2A6 P11509 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17899358 0.85 CYP11B1 (0.45) CYP11B1ALDH1A1MEN1KMT2AHPGD
SCHEMBL24174562 0.83 ALDH1A1 (0.59) CYP11B1ALDH1A1MEN1KMT2AHPGD
Biphenyl SCHEMBL4006358 0.83 ALDH1A1 (0.59) CYP11B1ALDH1A1MEN1KMT2AHPGD
SCHEMBL5851578 0.82 ALDH1A1 (0.63) CYP11B1ALDH1A1MEN1KMT2AHPGD
SCHEMBL23078456 0.82 ESR1 (0.39) CYP11B1ALDH1A1MEN1KMT2AHPGD
SCHEMBL25904437 0.81 CYP11B1 (0.39) CYP11B1ALDH1A1MEN1KMT2AHPGD
SCHEMBL10332129 0.80 CYP11B1 (0.51) CYP11B1ALDH1A1MEN1KMT2AHPGD
SCHEMBL23018789 0.80 HPRT1 (0.54) ALDH1A1MEN1KMT2AHPGDHSD17B10
SCHEMBL12520821 0.80 CYP11B1 (0.59) CYP11B1ALDH1A1MEN1KMT2AHPGD
SCHEMBL25899195 0.80 CYP11B1 (0.38) CYP11B1ALDH1A1MEN1KMT2AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021086142-A1 ORGANIC COMPOUND, ORGANIC LIGHT-EMITTING DIODE INCLUDING SAME, AND DISPLAY DEVICE INCLUDING ORGANIC LIGHT-EMITTING DIODE 솔브레인 주식회사 2021-05-06 WO disclosed
US-20120080667-A1 COMPOSITE MATERIAL, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-04-05 US disclosed
WO-2010062065-A2 NOVEL NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME 주식회사 엘지화학 (KR) 2010-06-03 WO disclosed
EP-1950194-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING THE SAME Idemitsu Kosan Co., Ltd. (JP) 2008-07-30 EP disclosed