⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL79028 | 0.77 | — | — | |
| SCHEMBL294198 | 0.74 | — | — | |
| SCHEMBL2540702 | 0.72 | ALOX15 (0.32) | — | |
| SCHEMBL292474 | 0.72 | ALOX15 (0.32) | — | |
| SCHEMBL1862141 | 0.72 | ALOX15 (0.32) | — | |
| SCHEMBL1678731 | 0.72 | ALOX15 (0.32) | — | |
| SCHEMBL7274009 | 0.72 | ALOX15 (0.32) | — | |
| SCHEMBL7691930 | 0.72 | ALOX15 (0.32) | — | |
| SCHEMBL7850745 | 0.72 | ALOX15 (0.32) | — | |
| SCHEMBL30548959 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 5557 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024099429-A1 | COMPOUND FOR REGULATING AND CONTROLLING ACTIVITY OF 15-PGDH AND PREPARATION METHOD THEREFOR | 赛诺哈勃药业（成都）有限公司 | 2024-05-16 | — | — | WO | claimed |
| CN-118005608-A | Triazole small molecular organic compound for inhibiting mitochondrial oxidative phosphorylation by specific targeting complex I and application thereof | 华东师范大学 | 2024-05-10 | — | — | CN | claimed |
| EP-4339188-A1 | QUINAZOLINE COMPOUND, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Shanghai Pharmaceuticals Holding Co., Ltd. (CN) | 2024-03-20 | — | — | EP | claimed |
| CN-117327000-A | Biphenyl tetrahydropyrrole compound and preparation method and application thereof | 海南因瑞生物医药科技有限公司 | 2024-01-02 | — | — | CN | claimed |
| CN-115232129-B | PARP1 selective inhibitor and preparation method and application thereof | 上海闻耐医药科技有限公司 | 2023-12-01 | — | — | CN | claimed |
| US-20230348421-A1 | 5-HT2A RECEPTOR INHIBITOR OR INVERSE AGONIST, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | LUYE INNOMIND PHARMA SHIJIAZHUANG CO., LTD. (CN) | 2023-11-02 | — | — | US | claimed |
| CN-114591312-B | Sulfone and sulfoxide compounds, preparation method and medical application thereof | 中国药科大学 | 2023-07-28 | — | — | CN | claimed |
| US-20230192620-A1 | ANILINE COMPOUND USED AS RORy REGULATOR | SHANGHAI LITEDD CO., LTD. (CN) | 2023-06-22 | — | — | US | claimed |
| EP-4186893-A1 | 5-HT2A RECEPTOR INHIBITOR OR INVERSE AGONIST, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | Geneora Pharma (Shijiazhuang) Co., Ltd. (CN) | 2023-05-31 | — | — | EP | claimed |
| EP-4151626-A1 | ANILINE COMPOUND USED AS RORy REGULATOR | Shanghai Litedd Co., Ltd. (CN) | 2023-03-22 | — | — | EP | claimed |
| EP-0499416-A2 | Pyridine compounds as angiotensin II antagonists, processes for their preparation and pharmaceutical compositions containing them | ZENECA LIMITED (GB) | 1992-08-19 | — | — | EP | claimed |
| EP-0495948-A1 | PROCESS FOR THE MANUFACTURE OF QUINOLINE DERIVATIVES | ZENECA LIMITED (GB) | 1992-07-29 | — | — | EP | claimed |
| US-5126344-A | Angiotensin antagonists | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-06-30 | — | — | US | claimed |
| EP-0487252-A1 | Quinoline and 1,5-Naphthyridine derivatives, process and intermediates for their preparation and pharmaceutical compositions containing them | ZENECA LIMITED (GB) | 1992-05-27 | — | — | EP | claimed |
| WO-1992002508-A1 | PROCESS FOR THE MANUFACTURE OF QUINOLINE DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-02-20 | — | — | WO | claimed |
| EP-0456442-A1 | Quinoline derivatives, process for their preparation and their use as medicaments | ZENECA LIMITED (GB) | 1991-11-13 | — | — | EP | claimed |
| EP-0454831-A1 | Diazine derivatives as angiotensin II receptor antagonists. | ICI PLC (GB) | 1991-11-06 | — | — | EP | claimed |
| WO-1991007404-A1 | DIAZINE DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-05-30 | — | — | WO | claimed |
| EP-0412848-A2 | Quinoline derivatives, process for their preparation and their use as medicaments | ZENECA LIMITED (GB) | 1991-02-13 | — | — | EP | claimed |
| EP-0370704-A2 | Aralkylamine derivatives, preparation thereof and fungicides containing the same | UBE INDUSTRIES, LTD. (JP) | 1990-05-30 | — | — | EP | claimed |