SCHEMBL10127239

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6158479	0.83	MAPK1 (0.59)	ALKROCK1SYKJAK2TYK2
	SCHEMBL328227	0.82	GRM4 (0.47)	ALKEML4ROCK1JAK2TYK2
	SCHEMBL283230	0.80	EML4 (0.66)	ALKEML4CAMK1DPDE4BROCK1
	SCHEMBL283909	0.78	ALK (0.70)	ALKEML4CAMK1DROCK1SYK
	SCHEMBL283908	0.78	ALK (0.70)	ALKEML4CAMK1DROCK1SYK
	SCHEMBL10127276	0.78	EML4 (0.60)	ALKEML4CAMK1DPDE4BROCK1
	SCHEMBL14955386	0.77	ALK (0.77)	ALKEML4CAMK1DROCK1SYK
	SCHEMBL10156720	0.76	ALK (0.67)	ALKEML4CAMK1DPDE4BROCK1
	SCHEMBL10129129	0.76	ALK (0.58)	ALKEML4CAMK1DROCK1SYK
	SCHEMBL10129000	0.76	EML4 (0.71)	ALKEML4CAMK1DPDE4BROCK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.