SCHEMBL1012773

SCHEMBL1012773

NNCC=CO

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9001348 0.97
SCHEMBL724589 0.72
SCHEMBL12113165 0.69
SCHEMBL15384248 0.69
SCHEMBL11808333 0.69
SCHEMBL88928 0.69
SCHEMBL525827 0.67
SCHEMBL461840 0.67
SCHEMBL7472367 0.67
SCHEMBL13601240 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 124 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113302171-A Hydrazine compositions with reduced vapor toxicity 航天喷气发动机洛克达因股份有限公司 2021-08-24 CN claimed
CN-104910035-B A kind of method that hydroxyalkyl amide is catalyzed and synthesized with supported solid 南京理工大学 2017-03-15 CN claimed
CN-104910035-A Method for catalytic synthesis of hydroxyalkylamide by using loaded solid alkali UNIV NANJING SCIENCE & TECH 2015-09-16 CN claimed
CN-100384847-C Adenosine a2a receptor antagonists SCHERING CORP (US) 2008-04-30 CN claimed
CN-1800186-A Adenosine a2a receptor antagonists SCHERING CORP (US) 2006-07-12 CN claimed
US-7067655-B2 preparation of furanyl, thienyl, pyridyl, pyridyl N-oxide, oxazolyl, phenyl, pyrrolyl or C4-C6 cycloalkenyl- substituted 5-amino-pyrazolo-[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidine adenosines prepared from 2-amino-4,6-dihydroxypyrimidine, POCl3 and dimethylformamide SCHERING CORPORATION (US) 2006-06-27 US claimed
EP-1283839-B1 ADENOSINE A2A RECEPTOR ANTAGONISTS SCHERING CORP (US) 2005-04-20 EP claimed
US-20050026932-A1 Adenosine A2a receptor antagonists SCHERING CORPORATION 2005-02-03 US claimed
WO-2004099299-A2 POROUS POLY(ARYL ETHER KETONE) MEMBRANES, PROCESSES FOR THEIR PREPARATION AND USE THEREOF POROGEN CORPORATION (US) 2004-11-18 WO claimed
US-20040222169-A1 Blending of polyether ketone polymers with polyimides, then shaping, depolymerization and removal of polyimide monomers, to form porometric materials such as sheets, tubes or fibers used for filtration or adsorption MASSACHUSETTS DEVELOPMENT FINANCE AGENCY 2004-11-11 US claimed
US-20040023997-A1 Adenosine A2a receptor antagonists MERCK SHARP & DOHME CORP. 2004-02-05 US claimed
CN-1451007-A Adenosine A2aReceptor antagonists SCHERING CORP (US) 2003-10-22 CN claimed
EP-1283839-A1 ADENOSINE A2A RECEPTOR ANTAGONISTS SCHERING CORPORATION (US) 2003-02-19 EP claimed
US-20020099061-A1 Adenosine A2a receptor antagonists MERCK SHARP & DOHME CORP. 2002-07-25 US claimed
WO-2001092264-A1 ADENOSINE A2A RECEPTOR ANTAGONISTS SCHERING CORPORATION (US) 2001-12-06 WO claimed
CN-1003301-B Chemical Purification Method of Ethylene Oxide 浙江大学 1989-02-15 CN claimed
CN-86103366-A The chemical purification method of oxyethane 1987-01-24 CN claimed
US-4524006-A Selected alkylhydrazine and hydroxyalkylhydrazine adducts of diisocyanates and their use as antioxidants OLIN CORPORATION (US) 1985-06-18 US claimed
US-4168292-A IN OIL WELLS PETROLITE CORPORATION (US) 1979-09-18 US claimed
US-11878284-B2 Mesoporous poly (aryl ether ketone) hollow fiber membranes and use thereof in mass transfer processes Avanpore LLC (US) 2024-01-23 US disclosed
CN-117199224-A Method for producing slurry composition and method for producing all-solid-state battery 丰田自动车株式会社 2023-12-08 CN disclosed
US-11786871-B2 Composite poly (aryl ether ketone) membranes, their preparation and use thereof Avanpore LLC (US) 2023-10-17 US disclosed
US-20230226500-A1 Composite Poly (Aryl Ether Ketone) Membranes, Their Preparation And Use Thereof Avanpore LLC (US) 2023-07-20 US disclosed
US-20230219062-A1 Mesoporous Poly (Aryl Ether Ketone) Hollow Fiber Membranes And Use Thereof In Mass Transfer Processes Avanpore LLC (US) 2023-07-13 US disclosed
US-11673099-B2 Composite poly (aryl ether ketone) membranes, their preparation and use thereof Avanpore LLC (US) 2023-06-13 US disclosed
US-11629239-B2 Preparation of mesoporous poly (aryl ether ketone) articles and use thereof Avanpore LLC (US) 2023-04-18 US disclosed
US-20230060660-A1 Mesoporous Poly (Aryl Ether Ketone) Hollow Fiber Membranes And Use Thereof In Mass Transfer Processes Avanpore LLC (US) 2023-03-02 US disclosed
US-20230059166-A1 Composite Poly (Aryl Ether Ketone) Membranes, Their Preparation And Use Thereof Avanpore LLC (US) 2023-02-23 US disclosed
US-20230050009-A1 Preparation Of Mesoporous Poly (Aryl Ether Ketone) Articles And Use Thereof Avanpore LLC (US) 2023-02-16 US disclosed
EP-4119217-A1 COMPOSITE POLY (ARYL ETHER KETONE) MEMBRANES THEIR PREPARATION AND USE THEREOF Avanpore LLC (US) 2023-01-18 EP disclosed
EP-4104917-A1 PREPARATION OF MESOPOROUS POLY (ARYL ETHER KETONE) ARTICLES AND USE THEREOF Avanpore LLC (US) 2022-12-21 EP disclosed
CN-113302171-B Hydrazine compositions with reduced vapor toxicity 航天喷气发动机洛克达因股份有限公司 2022-12-16 CN disclosed
CN-113302171-B Hydrazine compositions with reduced vapor toxicity 航天喷气发动机洛克达因股份有限公司 2022-12-16 CN disclosed
US-11511238-B1 Composite covalent organic framework membranes Avanpore LLC (US) 2022-11-29 US disclosed
CN-113574041-A Method for producing bisphenol and method for producing polycarbonate resin 三菱化学株式会社 2021-10-29 CN disclosed
CN-113302171-A Hydrazine compositions with reduced vapor toxicity 航天喷气发动机洛克达因股份有限公司 2021-08-24 CN disclosed
CN-113302171-A Hydrazine compositions with reduced vapor toxicity 航天喷气发动机洛克达因股份有限公司 2021-08-24 CN disclosed
US-10975037-B2 Phenyl substituted pyrazoles as modulators of RORγt JANSSEN PHARMACEUTICA NV (BE) 2021-04-13 US disclosed
CN-112566901-A Phenyl-substituted pyrazoles as modulators of ROR γ t 詹森药业有限公司 2021-03-26 CN disclosed
EP-3790865-A1 PHENYL SUBSTITUTED PYRAZOLES AS MODULATORS OF RORYT Janssen Pharmaceutica NV (BE) 2021-03-17 EP disclosed
WO-2020189201-A1 METHOD FOR PRODUCING BISPHENOL AND METHOD FOR PRODUCING POLYCARBONATE RESIN 三菱ケミカル株式会社 2020-09-24 WO disclosed
WO-2019243999-A1 PHENYL SUBSTITUTED PYRAZOLES AS MODULATORS OF RORYT JANSSEN PHARMACEUTICA NV (BE) 2019-12-26 WO disclosed
US-10376846-B2 Composite perfluorohydrocarbon membranes, their preparation and use POROGEN CORPORATION (US) 2019-08-13 US disclosed
CN-109096127-A Using silane coupling agent production by-product as the hydramine of raw material and preparation method and application 湖北鑫统领万象科技有限公司 2018-12-28 CN disclosed
EP-2763987-B1 HETEROCYCLYLPYRI(MI)DINYLPYRAZOLE AS FUNGICIDALS BAYER CROPSCIENCE AG (DE) 2018-07-18 EP disclosed
US-20170203257-A1 COMPOSITE PERFLUOROHYDROCARBON MEMBRANES, THEIR PREPARATION AND USE L'AIR LIQUIDE, SOCIETE ANONYME POUR L'ETUDE ET L'EXPLOITATION DES PROCEDES GEORGES CLAUDE (FR) 2017-07-20 US disclosed
US-9610547-B2 Composite perfluorohydrocarbon membranes, their preparation and use POROGEN CORPORATION (US) 2017-04-04 US disclosed
CN-104910035-B A kind of method that hydroxyalkyl amide is catalyzed and synthesized with supported solid 南京理工大学 2017-03-15 CN disclosed
EP-2177488-B1 METHOD FOR PRODUCING HYDRAULIC POWDER KAO CORP (JP) 2016-02-24 EP disclosed
CN-104910035-A Method for catalytic synthesis of hydroxyalkylamide by using loaded solid alkali UNIV NANJING SCIENCE & TECH 2015-09-16 CN disclosed
US-9023844-B2 Heterocyclylpyri (mi) dinylpyrazole as fungicidals BAYER INTELLECTUAL PROPERTY GMBH (DE) 2015-05-05 US disclosed
US-20140256677-A1 HETEROCYCLYLPYRI (MI) DINYLPYRAZOLE AS FUNGICIDALS BAYER INTELLECTUAL PROPERTY GMBH (DE) 2014-09-11 US disclosed
CN-104039785-A Heterocyclylpyrazoles as fungicides BAYER IP GMBH 2014-09-10 CN disclosed
EP-2763987-A1 HETEROCYCLYLPYRI (MI) DINYLPYRAZOLE AS FUNGICIDALS Bayer Intellectual Property GmbH (DE) 2014-08-13 EP disclosed
EP-2301901-B1 METHOD FOR PRODUCING HYDRAULIC POWDER KAO CORP (JP) 2014-03-26 EP disclosed
CN-102099311-B Method for producing hydraulic powder KAO CORP 2013-12-04 CN disclosed
US-8567703-B2 Method for producing hydraulic powder KAO CORPORATION (JP) 2013-10-29 US disclosed
CN-101784499-B Method for producing hydraulic powder KAO CORP 2013-06-19 CN disclosed
US-RE44205-E1 Adenosine A2a receptor antagonists MERCK SHARP & DOHME CORP. (US) 2013-05-07 US disclosed
WO-2013050437-A1 HETEROCYCLYLPYRI (MI) DINYLPYRAZOLE AS FUNGICIDALS BAYER INTELLECTUAL PROPERTY GMBH (DE) 2013-04-11 WO disclosed
CN-101784500-B Method for producing hydraulic powder KAO CORP 2012-12-12 CN disclosed
US-8322638-B2 Method for producing hydraulic powder KAO CORPORATION (JP) 2012-12-04 US disclosed
US-8235315-B2 Method for producing hydraulic powder KAO CORPORATION (JP) 2012-08-07 US disclosed
CN-102099311-A Method for producing hydraulic powder KAO CORP 2011-06-15 CN disclosed
US-20110120307-A1 Composite Perfluorohydrocarbon Membranes, Their Preparation and Use POROGEN CORPORATION (US) 2011-05-26 US disclosed
US-20110100264-A1 METHOD FOR PRODUCING HYDRAULIC POWDER KAO CORPORATION (JP) 2011-05-05 US disclosed
EP-2301901-A1 METHOD FOR PRODUCING HYDRAULIC POWDER Kao Corporation (JP) 2011-03-30 EP disclosed
US-20110005432-A1 METHOD FOR PRODUCING HYDRAULIC POWDER KAO CORPORATION (JP) 2011-01-13 US disclosed
US-20100319587-A1 METHOD FOR PRODUCING HYDRAULIC POWDER KAO CORPORATION (JP) 2010-12-23 US disclosed
CN-101784499-A Method for producing hydraulic powder KAO CORP 2010-07-21 CN disclosed
CN-101784500-A Method for producing hydraulic powder KAO CORP 2010-07-21 CN disclosed
EP-2177488-A1 METHOD FOR PRODUCING HYDRAULIC POWDER Kao Corporation (JP) 2010-04-21 EP disclosed
EP-2033955-A1 Urea derivatives of 1H-pyrazol-4-carboxylic acid with neutrophil chemotaxis inhibiting activity Universita' Degli Studi Di Genova (IT) 2009-03-11 EP disclosed
US-7368526-B2 Functionalized porous poly(aryl ether ketone) materials and their use POROGEN CORPORATION (US) 2008-05-06 US disclosed
CN-100384847-C Adenosine a2a receptor antagonists SCHERING CORP (US) 2008-04-30 CN disclosed
WO-2007149640-A2 COMPOSITE PERFLUOROHYDROCARBON MEMBRANES, THEIR PREPARATION AND USE POROGEN CORPORATION (US) 2007-12-27 WO disclosed
US-20070256969-A1 Composite Perfluorohydrocarbon Membranes, Their Preparation and Use POROGEN CORPORATION (US) 2007-11-08 US disclosed
US-20070129529-A1 Functionalized Porous Poly(Aryl Ether Ketone) Materials And Their Use MASSACHUSETTS DEVELOPMENT FINANCE AGENCY 2007-06-07 US disclosed
US-7176273-B2 Functionalized porous poly(aryl ether ketone) materials and their use POROGEN LLC (US) 2007-02-13 US disclosed
CN-1800186-A Adenosine a2a receptor antagonists SCHERING CORP (US) 2006-07-12 CN disclosed
US-7067655-B2 preparation of furanyl, thienyl, pyridyl, pyridyl N-oxide, oxazolyl, phenyl, pyrrolyl or C4-C6 cycloalkenyl- substituted 5-amino-pyrazolo-[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidine adenosines prepared from 2-amino-4,6-dihydroxypyrimidine, POCl3 and dimethylformamide SCHERING CORPORATION (US) 2006-06-27 US disclosed
US-20060094852-A1 Functionalized porous poly(aryl ether ketone) materials and their use MASSACHUSETTS DEVELOPMENT FINANCE AGENCY 2006-05-04 US disclosed
CN-1247588-C Adenosine A2aReceptor antagonists SCHERING CORP (US) 2006-03-29 CN disclosed
US-6897216-B2 Adenosine A2a receptor antagonists SCHERING CORPORATION (US) 2005-05-24 US disclosed
US-6887408-B2 Blending of polyether ketone polymers with polyimides, then shaping, depolymerization and removal of polyimide monomers, to form porometric materials such as sheets, tubes or fibers used for filtration or adsorption POROGEN LLC (US) 2005-05-03 US disclosed
EP-1283839-B1 ADENOSINE A2A RECEPTOR ANTAGONISTS SCHERING CORP (US) 2005-04-20 EP disclosed
US-20050026932-A1 Adenosine A2a receptor antagonists SCHERING CORPORATION 2005-02-03 US disclosed
WO-2004099299-A2 POROUS POLY(ARYL ETHER KETONE) MEMBRANES, PROCESSES FOR THEIR PREPARATION AND USE THEREOF POROGEN CORPORATION (US) 2004-11-18 WO disclosed
US-20040222169-A1 Blending of polyether ketone polymers with polyimides, then shaping, depolymerization and removal of polyimide monomers, to form porometric materials such as sheets, tubes or fibers used for filtration or adsorption MASSACHUSETTS DEVELOPMENT FINANCE AGENCY 2004-11-11 US disclosed
EP-1154868-A4 NON-CORROSIVE CLEANING COMPOSITION AND METHOD FOR REMOVING PLASMA ETCHING RESIDUES ARCH SPEC CHEM INC (US) 2004-03-24 EP disclosed
US-20040023997-A1 Adenosine A2a receptor antagonists MERCK SHARP & DOHME CORP. 2004-02-05 US disclosed
CN-1451007-A Adenosine A2aReceptor antagonists SCHERING CORP (US) 2003-10-22 CN disclosed
US-6630475-B2 5-amino-pyrazolo-(4, 3-e)-1,2,4-triazolo(1,5-c)pyrimidine adenosine A2a receptor antagonists; use in the treatment of central nervous system diseases, in particular Parkinson's disease SCHERING CORPORATION 2003-10-07 US disclosed
EP-1283839-A1 ADENOSINE A2A RECEPTOR ANTAGONISTS SCHERING CORPORATION (US) 2003-02-19 EP disclosed
EP-0897795-B1 Directly imageable raw plate for planographic printing plate TORAY INDUSTRIES (JP) 2002-12-04 EP disclosed
US-20020099061-A1 Adenosine A2a receptor antagonists MERCK SHARP & DOHME CORP. 2002-07-25 US disclosed
WO-2001092264-A1 ADENOSINE A2A RECEPTOR ANTAGONISTS SCHERING CORPORATION (US) 2001-12-06 WO disclosed
EP-1154868-A1 NON-CORROSIVE CLEANING COMPOSITION AND METHOD FOR REMOVING PLASMA ETCHING RESIDUES ARCH SPECIALTY CHEMICALS, INC. (US) 2001-11-21 EP disclosed
US-6194122-B1 Directly imageable waterless planographic printing plate TORAY INDUSTRIES, INC. (JP) 2001-02-27 US disclosed
US-6103680-A COMPRISING A HYDROXY-(LOWER ALKYL)-HYDRAZINE, WATER, AND AT LEAST ONE CARBOXYLIC ACID SELECTED FROM CITRIC ACID, LACTIC ACID, SUCCINIC ACID, TARTARIC ACID, ETHYLENEDIAMINETETRAACETIC ACID, NITRILOTRIACETIC ACID ARCH SPECIALTY CHEMICALS, INC. (US) 2000-08-15 US disclosed
WO-2000040347-A1 NON-CORROSIVE CLEANING COMPOSITION AND METHOD FOR REMOVING PLASMA ETCHING RESIDUES ARCH SPECIALTY CHEMICALS, INC. (US) 2000-07-13 WO disclosed
EP-0897795-A1 Directly imageable raw plate for planographic printing plate TORAY INDUSTRIES, INC. (JP) 1999-02-24 EP disclosed
US-5869710-A Polygdroxyalkylamidobetaines HOECHST AKTIENGESELLSCHAFT (DE) 1999-02-09 US disclosed
US-5760258-A SURFACTANTS; ESPECIALLYL FOR COSMETICS HOECHST AKTIENGESELLSCHAFT (DE) 1998-06-02 US disclosed
WO-1996004223-A1 REDUCED VOLATILITY SUBSTITUTED HYDRAZINE COMPOUNDS IN LIQUID PROPELLANTS OLIN CORPORATION (US) 1996-02-15 WO disclosed
US-5433802-A Hydroxy or cyano substituted hydrazines, nitrogen oxide oxidizers OLIN CORPORATION (US) 1995-07-18 US disclosed
US-4888244-A ELECTRODEPOSITION OF-CATIONIC RESIN, COATING WITH POLYISOCYANATE KANSAI PAINT CO., LTD. (JP) 1989-12-19 US disclosed
CN-1003301-B Chemical Purification Method of Ethylene Oxide 浙江大学 1989-02-15 CN disclosed
CN-1003301-B Chemical Purification Method of Ethylene Oxide 浙江大学 1989-02-15 CN disclosed
EP-0103381-B1 SUBSTITUTED ANTHRA(1,9-CD)PYRAZOL-6(2H)-ONES WARNER-LAMBERT COMPANY (US) 1987-09-23 EP disclosed
CN-86103366-A The chemical purification method of oxyethane 1987-01-24 CN disclosed
CN-86103366-A The chemical purification method of oxyethane 1987-01-24 CN disclosed
US-4556654-A ANTICARCINOGENIC, FUNGICIDES, ANTISEPTICS WARNER-LAMBERT COMPANY (US) 1985-12-03 US disclosed
US-4524006-A Selected alkylhydrazine and hydroxyalkylhydrazine adducts of diisocyanates and their use as antioxidants OLIN CORPORATION (US) 1985-06-18 US disclosed
US-4524006-A Selected alkylhydrazine and hydroxyalkylhydrazine adducts of diisocyanates and their use as antioxidants OLIN CORPORATION (US) 1985-06-18 US disclosed
US-4524006-A Selected alkylhydrazine and hydroxyalkylhydrazine adducts of diisocyanates and their use as antioxidants OLIN CORPORATION (US) 1985-06-18 US disclosed
EP-0103381-A1 Substituted anthra(1,9-cd)pyrazol-6(2H)-ones WARNER-LAMBERT COMPANY (US) 1984-03-21 EP disclosed
US-4271155-A Water soluble hydrazones of 3-formylrifamycin SV, antibacterial compositions thereof and method of use thereof GRUPPO LEPETIT S.P.A. (IT) 1981-06-02 US disclosed
EP-0025165-A1 Quaternary esters of hydroxyalkylamido amines, a process for their preparation and their utilization as fabric softening rinsing agents HOECHST AKTIENGESELLSCHAFT (DE) 1981-03-18 EP disclosed
US-4004007-A ANTIINFLAMMATORY AGENTS E. R. SQUIBB & SONS, INC. (US) 1977-01-18 US disclosed
US-4003890-A ANTIINFLAMMATORY E. R. SQUIBB & SONS, INC. (US) 1977-01-18 US disclosed
US-3962222-A HYPOTENSIVES, ANTIINFLAMMATORY AGENTS E. R. SQUIBB & SONS, INC. (US) 1976-06-08 US disclosed
US-3960848-A CENTRAL NERVOUS SYSTEM DEPRESSANT E. R. SQUIBB & SONS, INC. (US) 1976-06-01 US disclosed
US-3957762-A CENTRAL NERVOUS SYSTEM DEPRESSANTS E. R. SQUIBB & SONS, INC. (US) 1976-05-18 US disclosed
US-3957762-A CENTRAL NERVOUS SYSTEM DEPRESSANTS E. R. SQUIBB & SONS, INC. (US) 1976-05-18 US disclosed