⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL11365445 | 0.84 | ALOX15 (0.41) | — | |
| SCHEMBL37331 | 0.72 | — | — | |
| SCHEMBL37332 | 0.72 | — | — | |
| SCHEMBL8191518 | 0.72 | TSHR (0.33) | — | |
| SCHEMBL14030756 | 0.71 | — | — | |
| SCHEMBL15177364 | 0.71 | — | — | |
| SCHEMBL4061263 | 0.69 | — | — | |
| SCHEMBL21447547 | 0.69 | — | — | |
| SCHEMBL10117071 | 0.69 | — | — | |
| SCHEMBL362058 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101066950-A | 4-amino-5-methylpyrazole derivatives and process for producing the same | SANKYO AGRO CO LTD (JP) | 2007-11-07 | — | — | CN | disclosed |
| CN-101062918-A | 4-amino-5-methylpyrazole derivatives and process for producing the same | SANKYO AGRO CO LTD (JP) | 2007-10-31 | — | — | CN | disclosed |
| CN-101062917-A | 4-amino-5-methylpyrazole derivatives and process for producing the same | SANKYO AGRO CO LTD (JP) | 2007-10-31 | — | — | CN | disclosed |
| CN-1732155-A | 4-amino-5-methylpyrazole derivatives and process for producing the same | SANKYO AGRO CO LTD (JP) | 2006-02-08 | — | — | CN | disclosed |
| EP-0858459-B1 | NOVEL ACID PYRAZOLE DERIVATIVES, PREPARATION METHOD THEREFOR, USE THEREOF AS DRUGS, NOVEL USE THEREFOR, AND PHARMACEUTICAL COMPOSITIONS CONTAINING SUCH DERIVATIVES | AVENTIS PHARMA SA (FR) | 2002-09-04 | — | — | EP | disclosed |
| US-5942622-A | NOVEL COMPOUNDS FOR TREATING ILLNESS RESULTING FROM ABNORMAL STIMULATION OF ENDOTHELIAL RECEPTORS; FOR EXAMPLE: 4-((6-CHLORO-1,3-BENZODIOXOL-5-YL)METHYL)-1-(CYCLOHEXYLMETHYL) -3-(2-PYRIDINYL)-1H-PYRAZOLE-5-CARBOXYLATE | HOECHST MARION ROUSSEL (FR) | 1999-08-24 | — | — | US | disclosed |
| EP-0858459-A1 | NOVEL ACID PYRAZOLE DERIVATIVES, PREPARATION METHOD THEREFOR, USE THEREOF AS DRUGS, NOVEL USE THEREFOR, AND PHARMACEUTICAL COMPOSITIONS CONTAINING SUCH DERIVATIVES | HOECHST MARION ROUSSEL (FR) | 1998-08-19 | — | — | EP | disclosed |
| WO-1997015570-A1 | NOVEL ACID PYRAZOLE DERIVATIVES, PREPARATION METHOD THEREFOR, USE THEREOF AS DRUGS, NOVEL USE THEREFOR, AND PHARMACEUTICAL COMPOSITIONS CONTAINING SUCH DERIVATIVES | HOECHST MARION ROUSSEL (FR) | 1997-05-01 | — | — | WO | disclosed |
| EP-0443157-B1 | Stable dispersions of polyhydrazodicarbonamides useful in the preparation of polyurethane products having improved load-bearing capacity | MILES INC (US) | 1994-09-07 | — | — | EP | disclosed |
| US-5342855-A | Stable dispersions of polyhydrazodicarbonamides useful in the preparation of polyurethane products having improved load-bearing capacity | MILES INC. (US) | 1994-08-30 | — | — | US | disclosed |
| EP-0443157-A1 | Stable dispersions of polyhydrazodicarbonamides useful in the preparation of polyurethane products having improved load-bearing capacity | MILES INC. (US) | 1991-08-28 | — | — | EP | disclosed |
| US-4107102-A | POLY(ALKYLENE ETHER)POLYOL, HYDRAZINE DERIVATIVE, DIISOCYANATE, BLOWING AGENT | BAYER AKTIENGESELLSCHAFT (DE) | 1978-08-15 | — | — | US | disclosed |
| US-4094970-A | ELASTOMERIC POLYURETHANE-BASED ARTICLES HAVING AN INSECTICIDAL DEPOT GAS ACTION | BAYER AKTIENGESELLSCHAFT (DT) | 1978-06-13 | — | — | US | disclosed |