Sugi Predict

Sugi Predict / Compounds / SCHEMBL10128017

SCHEMBL10128017

SCHEMBL10128017

c1ccc2cc(-c3ccc(-c4cn5c(-c6ccc(-c7cccc8c7sc7ccccc78)cc6)nnc5c5ccccc45)cc3)ccc2c1

nearest known ligand 0.42

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ ALOX5 P09917 1/20 0.42
▸ PRKDC P78527 4/20 0.35
▸ S1PR5 Q9H228 7/20 0.33
▸ S1PR4 O95977 6/20 0.33
▸ PARP14 Q460N5 1/20 0.33
▸ AKT1 P31749 1/20 0.33
▸ HTT P42858 1/20 0.33
▸ PAX8 Q06710 1/20 0.33
▸ HSD11B1 P28845 1/20 0.32
▸ MAPT P10636 1/20 0.32
▸ MAPK9 P45984 1/20 0.32
▸ MAPK14 Q16539 1/20 0.32
▸ PIK3CD O00329 1/20 0.32
▸ PIK3CB P42338 1/20 0.32
▸ DNPH1 O43598 1/20 0.31
▸ PDE10A Q9Y233 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10128007 0.97 ALOX5 (0.46) ALOX5PRKDCS1PR5S1PR4PARP14
SCHEMBL10128012 0.90 ALOX5 (0.46) ALOX5PRKDCPARP14HTTPAX8
SCHEMBL10128015 0.89 ALOX5 (0.43) ALOX5PRKDCPARP14HTTPAX8
SCHEMBL10128013 0.89 ALOX5 (0.44) ALOX5PRKDCPARP14HTTPAX8
SCHEMBL10128000 0.88 ALOX5 (0.45) ALOX5PRKDCPARP14HTTPAX8
SCHEMBL10128010 0.87 ALOX5 (0.43) ALOX5PRKDCPARP14HTTPAX8
SCHEMBL10128026 0.86 ALOX5 (0.43) ALOX5PRKDCPARP14HTTPAX8
SCHEMBL10128009 0.84 ALOX5 (0.43) ALOX5PRKDCPARP14HTTPAX8
SCHEMBL10127977 0.84 ALOX5 (0.45) ALOX5PRKDCPARP14HTTPAX8
SCHEMBL10128028 0.84 ALOX5 (0.42) ALOX5PRKDCPARP14HTTPAX8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9034486-B2 Triazole derivative, heterocyclic compound, light-emitting element, light-emitting device, electronic device and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD (JP) 2015-05-19 — — US disclosed
US-9034486-B2 Triazole derivative, heterocyclic compound, light-emitting element, light-emitting device, electronic device and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD (JP) 2015-05-19 — — US disclosed
WO-2012017842-A1 TRIAZOLE DERIVATIVE, HETEROCYCLIC COMPOUND, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-02-09 — — WO disclosed
US-20120025697-A1 Triazole Derivative, Heterocyclic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-02-02 — — US disclosed
US-20120025697-A1 Triazole Derivative, Heterocyclic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-02-02 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120025697-A1 Triazole Derivative, Heterocyclic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device and Lighting Device HTR3D, KCNQ4, KCNQ3 ALOX5 1457/4885PRKDC 2900/4885S1PR5 4833/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.