SCHEMBL10128503

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10129016	0.98	ALK (0.72)	ALKEML4SYKFERMAPK1
	SCHEMBL10128907	0.91	ALK (0.75)	ALKEML4SYKFERMAPK1
	SCHEMBL10129001	0.90	ALK (0.70)	ALKEML4SYKFERMAPK1
	SCHEMBL10129004	0.90	ALK (0.70)	ALKEML4SYKFERMAPK1
	SCHEMBL10129019	0.90	ALK (0.75)	ALKEML4SYKFERMAPK1
	SCHEMBL10129018	0.89	ALK (0.71)	ALKEML4SYKFERMAPK1
	SCHEMBL10157468	0.88	EML4 (0.85)	ALKEML4FERROS1RET
	SCHEMBL10128872	0.86	ALK (0.86)	ALKEML4ROS1RETFLT3
	SCHEMBL10128859	0.86	ALK (0.86)	ALKEML4ROS1RETFLT3
	SCHEMBL286514	0.84	ALK (1.00)	ALKEML4ROS1RETFLT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.