Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 18/20 | 0.61 |
| ▸ | FER | P16591 | 2/20 | 0.44 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10128535 | 0.90 | SYK (0.64) | SYKFERZAP70 | |
| SCHEMBL10156251 | 0.90 | SYK (0.65) | SYKZAP70 | |
| SCHEMBL10128663 | 0.88 | SYK (0.61) | SYKFERZAP70 | |
| SCHEMBL10128413 | 0.85 | SYK (0.55) | SYK | |
| SCHEMBL10128677 | 0.85 | SYK (0.61) | SYKFER | |
| SCHEMBL10128685 | 0.83 | SYK (0.61) | SYKFERZAP70 | |
| SCHEMBL10128698 | 0.82 | SYK (0.64) | SYKFER | |
| SCHEMBL10126522 | 0.81 | MAPT (0.42) | — | |
| SCHEMBL2715387 | 0.81 | SYK (0.79) | SYKFERZAP70 | |
| SCHEMBL10128227 | 0.80 | SYK (0.67) | SYKZAP70 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8969336-B2 | Diamino heterocyclic carboxamide compound | ASTELLAS PHARMA INC. (JP) | 2015-03-03 | — | — | US | disclosed |
| US-20120040968-A1 | DIAMINO HETEROCYCLIC CARBOXAMIDE COMPOUND | WATERS TECHNOLOGIES CORPORATION (US) | 2012-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120040968-A1 | DIAMINO HETEROCYCLIC CARBOXAMIDE COMPOUND | EML4, ALK, ERBB4 | SYK 2200/4885FER 160/4885ZAP70 2470/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.