Sugi Predict

Sugi Predict / Compounds / SCHEMBL10128660

SCHEMBL10128660

SCHEMBL10128660

Cc1cccc2c1c1ccccc1n1c(-c3ccc(I)cc3)nnc21

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 3/20 0.42
▸ KDM4E B2RXH2 4/20 0.38
▸ HPGD P15428 4/20 0.38
▸ ALDH1A1 P00352 4/20 0.38
▸ MAPT P10636 3/20 0.38
▸ TP53 P04637 2/20 0.38
▸ TYMS P04818 1/20 0.37
▸ GABRA1 P14867 2/20 0.37
▸ GABRG2 P18507 2/20 0.37
▸ GABRB3 P28472 2/20 0.37
▸ GABRA5 P31644 2/20 0.37
▸ GABRA3 P34903 2/20 0.37
▸ GABRA2 P47869 2/20 0.37
▸ G6PD P11413 1/20 0.36
▸ PKM P14618 1/20 0.36
▸ ALOX12 P18054 1/20 0.36
▸ HKDC1 Q2TB90 1/20 0.36
▸ TDP1 Q9NUW8 1/20 0.36
▸ MEN1 O00255 1/20 0.35
▸ TSHR P16473 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10128480 0.87 POLB (0.42) POLBKDM4EHPGDALDH1A1MAPT
SCHEMBL10128894 0.86 POLB (0.42) POLBKDM4EHPGDALDH1A1MAPT
SCHEMBL10128682 0.85 POLB (0.43) POLBKDM4EHPGDALDH1A1MAPT
SCHEMBL10127791 0.85 POLB (0.43) POLBKDM4EHPGDALDH1A1MAPT
SCHEMBL10128626 0.83 POLB (0.53) POLBKDM4EHPGDALDH1A1MAPT
SCHEMBL10128640 0.82 POLB (0.52) POLBKDM4EHPGDALDH1A1MAPT
SCHEMBL10127427 0.79 ALOX5 (0.42) POLBKDM4EHPGDALDH1A1MAPT
SCHEMBL10127612 0.78 ALOX5 (0.41) POLBKDM4EHPGDALDH1A1MAPT
SCHEMBL10128662 0.78 POLB (0.46) POLBKDM4EHPGDALDH1A1MAPT
SCHEMBL10128658 0.76 POLB (0.44) POLBKDM4EHPGDALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9034486-B2 Triazole derivative, heterocyclic compound, light-emitting element, light-emitting device, electronic device and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD (JP) 2015-05-19 — — US disclosed
US-9034486-B2 Triazole derivative, heterocyclic compound, light-emitting element, light-emitting device, electronic device and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD (JP) 2015-05-19 — — US disclosed
WO-2012017842-A1 TRIAZOLE DERIVATIVE, HETEROCYCLIC COMPOUND, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-02-09 — — WO disclosed
US-20120025697-A1 Triazole Derivative, Heterocyclic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-02-02 — — US disclosed
US-20120025697-A1 Triazole Derivative, Heterocyclic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-02-02 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120025697-A1 Triazole Derivative, Heterocyclic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device and Lighting Device HTR3D, KCNQ4, KCNQ3 POLB 3317/4885KDM4E 2008/4885HPGD 1148/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.