SCHEMBL10128992

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10128906	0.92	EML4 (0.78)	EML4ALKAXLRETROS1
	SCHEMBL10128617	0.90	EML4 (0.81)	EML4ALKAXLRETROS1
	SCHEMBL10128905	0.89	EML4 (0.79)	EML4ALKAXLRETROS1
	SCHEMBL10128981	0.89	EML4 (0.79)	EML4ALKAXLRETROS1
	SCHEMBL10128983	0.88	EML4 (0.77)	EML4ALKAXLRETROS1
	SCHEMBL10128817	0.87	ALK (0.82)	EML4ALKAXLRETROS1
	SCHEMBL10157468	0.87	EML4 (0.85)	EML4ALKAXLRETROS1
	SCHEMBL10129011	0.87	EML4 (0.75)	EML4ALKAXLRETROS1
	SCHEMBL286514	0.86	ALK (1.00)	EML4ALKRETROS1FLT3
	SCHEMBL10128872	0.86	ALK (0.86)	EML4ALKAXLRETROS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.