SCHEMBL10129083

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10129084	0.97	EML4 (0.64)	EML4ALKCDK1CDK2MTOR
	SCHEMBL10129082	0.94	EML4 (0.67)	EML4ALKCAMK1DROCK1SYK
	SCHEMBL10129076	0.92	EML4 (0.62)	EML4ALKCAMK1DROCK1SYK
	SCHEMBL10129074	0.90	EML4 (0.67)	EML4ALKCAMK1DROCK1SYK
	SCHEMBL10156862	0.89	EML4 (0.66)	EML4ALKCAMK1DROCK1SYK
	SCHEMBL10129080	0.89	ALK (0.66)	EML4ALKCDK1CDK2CAMK1D
	SCHEMBL10129088	0.88	EML4 (0.64)	EML4ALKCAMK1DROCK1SYK
	SCHEMBL10129077	0.88	EML4 (0.64)	EML4ALKCAMK1DROCK1SYK
	SCHEMBL10129000	0.86	EML4 (0.71)	EML4ALKCAMK1DROCK1SYK
	SCHEMBL10129086	0.85	EML4 (0.63)	EML4ALKCAMK1DROCK1SYK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.