⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10698910 | 0.79 | DAO (0.32) | — | |
| SCHEMBL17471234 | 0.75 | — | — | |
| SCHEMBL20993356 | 0.75 | HDAC8 (0.31) | — | |
| Hydrochloric Acid SCHEMBL30556225 | 0.70 | DAO (0.33) | — | |
| SCHEMBL7778310 | 0.68 | GAA (0.31) | — | |
| SCHEMBL21723091 | 0.59 | — | — | |
| SCHEMBL20993530 | 0.59 | — | — | |
| SCHEMBL2006150 | 0.58 | DAO (0.32) | — | |
| SCHEMBL2973140 | 0.58 | — | — | |
| SCHEMBL47202 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1028475-C | Pyrrole insecticides | RHONE POULENC AGROCHIMIE (FR) | 1995-05-24 | — | — | CN | claimed |
| CN-1043500-A | PYRROLE INSECTICIDES | RHONE POULENC AGROCHIMIE (FR) | 1990-07-04 | — | — | CN | claimed |
| US-20210145824-A1 | MODULATORS OF CELLULAR ADHESION | NOVARTIS PHARMACEUTICALS CORPORATION (US) | 2021-05-20 | — | — | US | disclosed |
| US-20190134022-A1 | MODULATORS OF CELLULAR ADHESION | SARCODE BIOSCIENCE INC. (US) | 2019-05-09 | — | — | US | disclosed |
| CN-105358555-B | Condensed heterocyclic compound and pest control use thereof | 住友化学株式会社 | 2018-01-30 | — | — | CN | disclosed |
| WO-2017101890-A1 | SPIROKETAL DERIVATIVE, PREPARATION METHOD THEREFOR AND APPLICATION | 上海艾力斯医药科技有限公司 | 2017-06-22 | — | — | WO | disclosed |
| CN-105246876-B | Condensed heterocyclic compound and pest control use thereof | 住友化学株式会社 | 2017-06-16 | — | — | CN | disclosed |
| CN-103717598-B | Fused heterocyclic compound and the purposes for Pest control thereof | 住友化学株式会社 | 2016-12-07 | — | — | CN | disclosed |
| CN-104507911-B | Amide compound | 住友化学株式会社 | 2016-11-16 | — | — | CN | disclosed |
| CN-104334552-B | Fused heterocyclic compound | 住友化学株式会社 | 2016-08-31 | — | — | CN | disclosed |
| US-20160074381-A1 | MODULATORS OF CELLULAR ADHESION | SARCODE BIOSCIENCE INC. (US) | 2016-03-17 | — | — | US | disclosed |
| US-20100093693-A1 | MODULATORS OF CELLULAR ADHESION | BAUSCH + LOMB IRELAND LIMITED (IE) | 2010-04-15 | — | — | US | disclosed |
| US-20080182839-A1 | MODULATORS OF CELLULAR ADHESION | SUNESIS PHARMACEUTICALS, INC. (US) | 2008-07-31 | — | — | US | disclosed |
| US-20080182839-A1 | MODULATORS OF CELLULAR ADHESION | SUNESIS PHARMACEUTICALS, INC. (US) | 2008-07-31 | — | — | US | disclosed |
| US-20080176896-A1 | Modulators of cellular adhesion | BAUSCH + LOMB IRELAND LIMITED (IE) | 2008-07-24 | — | — | US | disclosed |
| US-7314938-B2 | Immune and/or inflammatory disorders; autoimmune disorders; disorders mediated by the CD11/CD18 family of cellular adhesion molecules (e.g., LFA-1); antagonize CD11/CD18 receptors associated with leukocytes. | SUNESIS PHARMACEUTICALS, INC. (US) | 2008-01-01 | — | — | US | disclosed |
| US-7314938-B2 | Immune and/or inflammatory disorders; autoimmune disorders; disorders mediated by the CD11/CD18 family of cellular adhesion molecules (e.g., LFA-1); antagonize CD11/CD18 receptors associated with leukocytes. | SUNESIS PHARMACEUTICALS, INC. (US) | 2008-01-01 | — | — | US | disclosed |
| CN-1028475-C | Pyrrole insecticides | RHONE POULENC AGROCHIMIE (FR) | 1995-05-24 | — | — | CN | disclosed |
| CN-1043500-A | PYRROLE INSECTICIDES | RHONE POULENC AGROCHIMIE (FR) | 1990-07-04 | — | — | CN | disclosed |
| EP-0372982-A2 | Pyrrole insecticides | RHONE-POULENC AGROCHIMIE (FR) | 1990-06-13 | — | — | EP | disclosed |