Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.32 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.32 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10129807 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL30556225 | 0.74 | DAO (0.33) | DAOHDAC8HDAC6AURKAAURKB | |
| SCHEMBL17471234 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL11060860 | 0.72 | — | — | |
| SCHEMBL10383537 | 0.71 | — | — | |
| SCHEMBL2973140 | 0.61 | — | — | |
| SCHEMBL194263 | 0.61 | — | — | |
| SCHEMBL1568292 | 0.61 | — | — | |
| SCHEMBL28959138 | 0.59 | — | — | |
| SCHEMBL1797065 | 0.59 | MCL1 (0.36) | DAOHDAC8HDAC6AURKAAURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0282692-A1 | Substituted hydroxy-azolylketones | BAYER AG (DE) | 1988-09-21 | — | — | EP | disclosed |
| EP-0234499-A2 | Antifungal azolylpropanol derivatives | SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) | 1987-09-02 | — | — | EP | disclosed |
| US-4291047-A | Combating fungi with α-azolyl-β-hydroxy-ketones | BAYER AKTIENGESELLSCHAFT (DE) | 1981-09-22 | — | — | US | disclosed |
| US-4251540-A | Combating crop damaging fungi with α-(4-biphenylyl)-benzyl-azolium salts | BAYER AKTIENGESELLSCHAFT (DE) | 1981-02-17 | — | — | US | disclosed |
| US-4243670-A | MICROBORICIDES; FUNGICIDES; SPORICIDES; HYGIENE | BAYER AKTIENGESELLSCHAFT (DE) | 1981-01-06 | — | — | US | disclosed |
| US-4118487-A | ANTIMICROBIAL AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1978-10-03 | — | — | US | disclosed |
| US-4118487-A | ANTIMICROBIAL AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1978-10-03 | — | — | US | disclosed |
| US-4049418-A | APPLYING A 5-AZOLYL-(A,D)-DIBENZOCYCLOHEPTENE | BAYER AKTIENGESELLSCHAFT (DT) | 1977-09-20 | — | — | US | disclosed |
| US-3872117-A | PHENYL-IMIDAZOLYL ACETIC ACID AMINO ALKANOL ESTERS AND AMIDES | BAYER AG | 1975-03-18 | — | — | US | disclosed |