Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 16/20 | 0.64 |
| ▸ | FLT1 | P17948 | 15/20 | 0.64 |
| ▸ | KIT | P10721 | 3/20 | 0.64 |
| ▸ | ABL1 | P00519 | 2/20 | 0.64 |
| ▸ | CSF1R | P07333 | 2/20 | 0.64 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.64 |
| ▸ | FLT4 | P35916 | 2/20 | 0.64 |
| ▸ | EGFR | P00533 | 1/20 | 0.64 |
| ▸ | BRAF | P15056 | 1/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.52 |
| ▸ | IGF1R | P08069 | 1/20 | 0.49 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.49 |
| ▸ | TEK | Q02763 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1013084 | 1.00 | KDR (0.64) | KDRFLT1KITABL1CSF1R | |
| Hydrochloric Acid SCHEMBL1039252 | 0.99 | KDR (0.63) | KDRFLT1KITABL1CSF1R | |
| Hydrochloric Acid SCHEMBL1011091 | 0.99 | KDR (0.63) | KDRFLT1KITABL1CSF1R | |
| SCHEMBL4978394 | 0.86 | KDR (0.74) | KDRFLT1KITABL1CSF1R | |
| SCHEMBL4981328 | 0.84 | KDR (0.71) | KDRFLT1KITABL1CSF1R | |
| SCHEMBL4979620 | 0.84 | KDR (0.75) | KDRFLT1KITABL1CSF1R | |
| SCHEMBL1009579 | 0.84 | KDR (0.70) | KDRFLT1KITABL1CSF1R | |
| SCHEMBL4979990 | 0.82 | KDR (0.71) | KDRFLT1KITABL1CSF1R | |
| SCHEMBL1012167 | 0.82 | KDR (0.65) | KDRFLT1KITABL1CSF1R | |
| SCHEMBL1041264 | 0.81 | KDR (0.64) | KDRFLT1KITABL1CSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2269988-B1 | Anthranilic acid amides and pharmaceutical use thereof | NOVARTIS AG (CH) | 2012-05-23 | — | — | EP | disclosed |
| EP-1446381-B1 | ANTHRANILIC ACID AMIDES AND PHARMACEUTICAL USE THEREOF | NOVARTIS AG (CH) | 2011-01-05 | — | — | EP | disclosed |
| EP-2269988-A2 | Anthranilic acid amides and pharmaceutical use thereof | Novartis AG (CH) | 2011-01-05 | — | — | EP | disclosed |
| US-7067543-B2 | Anthranilic acid amides and pharmaceutical use thereof | NOVARTIS AG (CH) | 2006-06-27 | — | — | US | disclosed |
| US-20040248947-A1 | Anthranilic acid amides and pharmaceutical use thereof | NOVARTIS AG (CH) | 2004-12-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040248947-A1 | Anthranilic acid amides and pharmaceutical use thereof | AFF1, FFAR1, FFAR2 | KDR 847/4885FLT1 214/4885KIT 4113/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.