Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 6/20 | 0.41 |
| ▸ | NQO2 | P16083 | 5/20 | 0.41 |
| ▸ | TLR4 | O00206 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | DRD5 | P21918 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
| ▸ | CTSV | O60911 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10132690 | 0.95 | CYP19A1 (0.43) | CYP19A1NQO2TLR4ATMALDH1A1 | |
| SCHEMBL10163285 | 0.91 | CYP19A1 (0.41) | CYP19A1NQO2TLR4ALDH1A1HTT | |
| SCHEMBL10161775 | 0.85 | CYP19A1 (0.43) | CYP19A1NQO2ATMALDH1A1KDM4E | |
| SCHEMBL10132879 | 0.78 | TDP1 (0.48) | CYP19A1NQO2ATMKDM4EMAPT | |
| SCHEMBL10132697 | 0.77 | CYP19A1 (0.41) | CYP19A1NQO2ATMALDH1A1SMN1; SMN2 | |
| SCHEMBL10132674 | 0.77 | CYP19A1 (0.37) | CYP19A1NQO2ALDH1A1KDM4EKMT2A | |
| SCHEMBL10132646 | 0.76 | CYP19A1 (0.40) | CYP19A1NQO2ATMALDH1A1SMN1; SMN2 | |
| SCHEMBL10132804 | 0.74 | CYP19A1 (0.39) | CYP19A1NQO2ATMALDH1A1 | |
| SCHEMBL10132743 | 0.74 | RET (0.45) | CYP19A1NQO2ATMSMN1; SMN2KMT2A | |
| SCHEMBL10132849 | 0.73 | KCNA3 (0.42) | CYP19A1NQO2ALDH1A1HTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8741917-B2 | Benzo [C] phenanthridines as antimicrobial agents | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2014-06-03 | — | — | US | disclosed |
| US-20120022061-A1 | BENZO [C] PHENANTHRIDINES AS ANTIMICROBIAL AGENTS | RUGTERS, THE STATE UNIVERSITY OF NEW JERSEY | 2012-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120022061-A1 | BENZO [C] PHENANTHRIDINES AS ANTIMICROBIAL AGENTS | CCNT1, XPO4, XDH | CYP19A1 596/4885NQO2 50/4885TLR4 504/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.